Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Wang, Mitchell K. License Attribution 3.0 United States

Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

Creator:

Wang, Zhixing, Zhang, Ling-juan, Guha, Gunjan, Li, Shan, Kyrylkova, Kateryna, Kioussi, Chrissa, Leid, Mark, Ganguli-Indra, Gitali, and Indra, Arup K.

Abstract:

Background: Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal differentiation, as well as altered lipid composition during development. However, little is known about the role of Ctip2...

Resource Type:

Article

Full Text:

Leid1,2,3, Gitali Ganguli-Indra1,2, Arup K. Indra1,2,3,4* 1 Department of Pharmaceutical Sciences, College