Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Zhang, Zhi License Attribution 3.0 United States

Length Bias Correction in Gene Ontology Enrichment Analysis Using Logistic Regression

Creator:

Mi, Gu, Di, Yanming, Emerson, Sarah, Cumbie, Jason S., and Chang, Jeff H.

Abstract:

When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called "length bias", will influence subsequent analyses such as Gene Ontology enrichment analysis. In the presence of length bias, Gene Ontology...

Resource Type:

Article

Full Text:

analysis for RNA-seq: accounting for selection bias. Genome Biol 11: R14. 11. Gao L, Fang Z, Zhang K, Zhi