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Automated and Accurate Estimation of Gene Family Abundance from Shotgun Metagenomes

Creator:

Nayfach, Stephen, Bradley, Patrick H., Wyman, Stacia K., Laurent, Timothy J., Williams, Alex, Eisen, Jonathan A., Pollard, Katherine S., and Sharpton, Thomas J.

Abstract:

Shotgun metagenomic DNA sequencing is a widely applicable tool for characterizing the functions that are encoded by microbial communities. Several bioinformatic tools can be used to functionally annotate metagenomes, allowing researchers to draw inferences about the functional potential of the community and to identify putative functional biomarkers. However, little is...

Resource Type:

Article

Full Text:

Metagenomes Stephen Nayfach1, Patrick H. Bradley1, Stacia K. Wyman1, Timothy J. Laurent1¤, Alex Williams1