Index Catalog // ScholarsArchive@OSU

Uncovering the Hidden Excited State toward Fluorescence of an Intracellular pH Indicator

Creator:: Tang, Longteng, Zhu, Liangdong, Wang, Yanli, and Fang, Chong
Abstract:: Intracellular pH (pH(i)) imaging is of paramount importance for life sciences. In this work, we implement the ultrafast electronic and stimulated Raman spectroscopies to unravel the fluorescence mechanism of an excitation-ratiometric pH(i) indicator in basic aqueous solution. After photoexcitation of the pH(i) indicator HPTS, a hidden charge-transfer (CT) state following...
Resource Type:: Article
Full Text:: formation on the 700 fs time scale. Dynamic correlation with the other excited-state Raman marker bands

Excited State Structural Evolution of a GFP Single-Site Mutant Tracked by Tunable Femtosecond-Stimulated Raman Spectroscopy

Creator:: Tang, Longteng, Zhu, Liangdong, Taylor, Miles A., Wang, Yanli, Remington, S. James, and Fang, Chong
Abstract:: Tracking vibrational motions during a photochemical or photophysical process has gained momentum, due to its sensitivity to the progression of reaction and change of environment. In this work, we implemented an advanced ultrafast vibrational technique, femtosecond-stimulated Raman spectroscopy (FSRS), to monitor the excited state structural evolution of an engineered green...
Resource Type:: Article
Full Text:: achieve high time resolution (<25 fs) and spectral resolution (<10 cm−1) in tracking photoinduced excited

Watching an Engineered Calcium Biosensor Glow: Altered Reaction Pathways before Emission

Creator:: Tachibana, Sean R., Tang, Longteng, Zhu, Liangdong, Liu, Weimin, Wang, Yanli, and Fang, Chong
Abstract:: Biosensors have become an indispensable tool set in life sciences. Among them, fluorescent protein-based biosensors have great biocompatibility and tunable emission properties but their development is largely on trial and error. To facilitate a rational design, we implement tunable femtosecond stimulated Raman spectroscopy, aided by transient absorption and quantum calculations,...
Resource Type:: Article
Full Text:: competing pathways on the native femtosecond (fs) to picosecond (ps) time scales, one can rationally

Modeling multidisciplinary design with multiagent learning

Creator:: Hulse, Daniel, Tumer, Kagan, Hoyle, Christopher, and Tumer, Irem
Abstract:: Complex engineered systems design is a collaborative activity. To design a system, experts from the relevant disciplines must work together to create the best overall system from their individual components. This situation is analogous to a multiagent system in which agents solve individual parts of a larger problem in a...
Resource Type:: Article
Full Text:: 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54

Femtosecond Stimulated Raman Line Shapes: Dependence on Resonance Conditions of Pump and Probe Pulses

Creator:: Chen, Cheng, Zhu, Liang-dong, and Fang, Chong
Abstract:: Resonance enhancement has been increasingly employed in the emergent femtosecond stimulated Raman spectroscopy (FSRS) to selectively monitor molecular structure and dynamics with improved spectral and temporal resolutions and signal-to-noise ratios. Such joint efforts by the technique- and application-oriented scientists and engineers have laid the foundation for exploiting the tunable FSRS...
Resource Type:: Article
Full Text:: the 4 W output), 800 nm fundamental pulse with 35 femtosecond (fs) duration of a mode-locked

Structure and role for active site lid of lactate monooxygenase from Mycobacterium smegmatis

Creator:: Kean, Kelsey M. and Karplus, P. Andrew
Abstract:: Lactate monooxygenase (LMO) catalyzes the FMN-dependent "coupled" oxidation of lactate and O-2 to acetate, carbon dioxide, and water, involving pyruvate and hydrogen peroxide as enzyme-bound intermediates. Other alpha-hydroxy acid oxidase family members follow an "uncoupled pathway," wherein the alpha-keto acid product quickly dissociates before the reduced flavin reacts with oxygen....
Resource Type:: Article
Full Text:: oxidation of lactic acid by Mycobacterium phlei. Biochem J. 41:145-51. 2. Ghisla S, Massey V. L-Lactate

Genetic evidence for alloparental care and frequent multiple paternity in the brooding sea star (Leptasterias sp.)

Creator:: Barreto, Felipe S. and Bauer, Kristofer K.
Abstract:: Echinoderms form an abundant and ecologically important group of marine animals, and they are found in nearly every marine environment, from shallow tropical waters to deep polar benthos and even in the pelagic zone. They exhibit a wide diversity of reproductive strategies that range from broadcasting millions of gametes, with...
Resource Type:: Article
Full Text:: 280:20122919. https ://doi. org/10.1111/mec.12009 Barreto FS, Avise JC (2008) Polygynandry and

Immunology beliefs as a factor in vaccine opposition among complementary and alternative medical providers

Creator:: Bean, Sandra J. and Catania, Joseph A.
Abstract:: Objectives: Parental pediatric vaccine decisions are influenced by parents' health provider networks. Complementary and alternative medical providers may be key influences in the networks of those parents who do not vaccinate their children. Methods: From March to July 2013, we conducted semi-structured interviews of Oregon complementary and alternative medical providers...
Resource Type:: Article
Full Text:: . Bean and Catania 5 T ab le 3 . Im m un e an d va cc in e be lie fs o f O re go n co

Competing tradeoffs between increasing marine mammal predation and fisheries harvest of Chinook salmon

Creator:: Chasco, Brandon E., Kaplan, Isaac C., Thomas, Austen C., Acevedo-Gutiérrez, Alejandro, Noren, Dawn P., Ford, Michael J., Hanson, M. Bradley, Scordino, Jonathan J., Jeffries, Steven J., Marshall, Kristin N., Shelton, Andrew O., Matkin, Craig, Burke, Brian J., and Ward, Eric J.
Abstract:: Many marine mammal predators, particularly pinnipeds, have increased in abundance in recent decades, generating new challenges for balancing human uses with recovery goals via ecosystem-based management. We used a spatio-temporal bioenergetics model of the Northeast Pacific Ocean to quantify how predation by three species of pinnipeds and killer whales (Orcinus...
Resource Type:: Article
Full Text:: defined as, = ∑ ∑ NC ED EC FS (5) p h j r o m y t a s i p h j y t s i a h r o t a p h j r o y t m a

Competing tradeoffs between increasing marine mammal predation and fisheries harvest of Chinook salmon

Creator:: Acevedo-Gutiérrez, Alejandro, Chasco, Brandon E., Ward, Eric J., Ford, Michael J., Shelton, Andrew O., Thomas, Austen C., Burke, Brian J., Marshall, Kristin N., Matkin, Craig, Jeffries, Steven J., Noren, Dawn P., Kaplan, Isaac C., Scordino, Jonathan J., and Hanson, M. Bradley
Abstract:: Many marine mammal predators, particularly pinnipeds, have increased in abundance in recent decades, generating new challenges for balancing human uses with recovery goals via ecosystem-based management. We used a spatio-temporal bioenergetics model of the Northeast Pacific Ocean to quantify how predation by three species of pinnipeds and killer whales (Orcinus...
Resource Type:: Article
Full Text:: defined as, = ∑ ∑ NC ED EC FS (5) p h j r o m y t a s i p h j y t s i a h r o t a p h j r o y t m a

ScholarsArchive@OSU

Uncovering the Hidden Excited State toward Fluorescence of an Intracellular pH Indicator

Excited State Structural Evolution of a GFP Single-Site Mutant Tracked by Tunable Femtosecond-Stimulated Raman Spectroscopy

Watching an Engineered Calcium Biosensor Glow: Altered Reaction Pathways before Emission

Modeling multidisciplinary design with multiagent learning

Femtosecond Stimulated Raman Line Shapes: Dependence on Resonance Conditions of Pump and Probe Pulses

Structure and role for active site lid of lactate monooxygenase from Mycobacterium smegmatis

Genetic evidence for alloparental care and frequent multiple paternity in the brooding sea star (Leptasterias sp.)

Immunology beliefs as a factor in vaccine opposition among complementary and alternative medical providers

Competing tradeoffs between increasing marine mammal predation and fisheries harvest of Chinook salmon

Competing tradeoffs between increasing marine mammal predation and fisheries harvest of Chinook salmon

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