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Myosin-Powered Membrane Compartment Drives Cytoplasmic Streaming, Cell Expansion and Plant Development

Creator:: Peremyslov, Valera V., Cole, Rex A., Fowler, John E., and Dolja, Valerian V.
Abstract:: Using genetic approaches, particle image velocimetry and an inert tracer of cytoplasmic streaming, we have made a mechanistic connection between the motor proteins (myosins XI), cargo transported by these motors (distinct endomembrane compartment defined by membrane-anchored MyoB receptors) and the process of cytoplasmic streaming in plant cells. It is shown...
Resource Type:: Article
Full Text:: Cytoplasmic Streaming, Cell Expansion and Plant Development Peremyslov, V. V., Cole, R. A., Fowler, J. E

Targeting an Essential GTPase Obg for the Development of Broad-Spectrum Antibiotics

Creator:: Bonventre, Josephine A., Zielke, Ryszard A., Korotkov, Konstantin V., and Sikora, Aleksandra E.
Abstract:: A promising new drug target for the development of novel broad-spectrum antibiotics is the highly conserved small GTPase Obg (YhbZ, CgtA), a protein essential for the survival of all bacteria including Neisseria gonorrhoeae (GC). GC is the agent of gonorrhea, a prevalent sexually transmitted disease resulting in serious consequences on...
Resource Type:: Article
Full Text:: -Spectrum Antibiotics Josephine A. Bonventre1, Ryszard A. Zielke1, Konstantin V. Korotkov2, Aleksandra E

High resolution lake sediment record reveals self-organized criticality in erosion processes regulated by internal feedbacks

Creator:: Colombaroli, D., Gavin, D. G., Morey, A. E., and Thorndycraft, V. R.
Abstract:: Reconstruction of high-frequency erosion variability beyond the instrumental record requires well-dated, high-resolution proxies from sediment archives. We used computed tomography (CT) scans of finely laminated silt layers from a lake-sediment record in southwest Oregon to quantify the magnitude of natural landscape erosion events over the last 2000years in order to...
Resource Type:: Article
Full Text:: estimated by a high-resolution record 22 23 Corresponding Author: Daniele Colombaroli

Swing-Leg Trajectory of Running Guinea Fowl Suggests Task-Level Priority of Force Regulation Rather than Disturbance Rejection

Creator:: Blum, Yvonne, Vejdani, Hamid R., Birn-Jeffery, Aleksandra V., Hubicki, Christian M., Hurst, Jonathan W., and Daley, Monica A.
Abstract:: To achieve robust and stable legged locomotion in uneven terrain, animals must effectively coordinate limb swing and stance phases, which involve distinct yet coupled dynamics. Recent theoretical studies have highlighted the critical influence of swing-leg trajectory on stability, disturbance rejection, leg loading and economy of walking and running. Yet, simulations...
Resource Type:: Article

Scaling up sustainability in commodity agriculture: Transferability of governance mechanisms across the coffee and cattle sectors in Brazil

Creator:: Hajjar, R., Newton, P., Adshead, D., Bogaerts, M., Maguire-Rajpaul, V. A., Pinto, L. F. G., McDermott, C. L., Milder, J. C., Wollenberg, E., and Agrawal, A.
Abstract:: A number of governance mechanisms address socio-environmental challenges associated with commodity agriculture in tropical forested countries. Governance mechanisms that prove effective in one agricultural sector are often applied to other sectors as well. For example, voluntary certification programs have been adopted by producers of commodities as diverse as beef, coffee,...
Resource Type:: Article
Full Text:: coffee and cattle sectors in Brazil R. Hajjar a, b, *, 1, P. Newton a, c, 1, D. Adshead d, M. Bogaerts a

Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon

Creator:: Rajendran, Praveen, Dashwood, Wan-Mohaiza, Li, Li, Kang, Yuki, Kim, Eunah, Johnson, Gavin, Fischer, Kay A., Löhr, Christiane V., Williams, David E., Ho, Emily, Yamamoto, Masayuki, Lieberman, David A., and Dashwood, Roderick H.
Abstract:: Background: The dietary agent sulforaphane (SFN) has been reported to induce nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)-dependent pathways as well as inhibiting histone deacetylase (HDAC) activity. The current investigation sought to examine the relationships between Nrf2 status and HDAC expression in preclinical and translational studies. Results: Wild type...
Resource Type:: Article

Finding Our Way through Phenotypes

Creator:: Deans, Andrew R., Lewis, Suzanna E., Huala, Eva, Anzaldo, Salvatore S., Ashburner, Michael, Balhoff, James P., Blackburn, David C., Blake, Judith A., Burleigh, J. Gordon, Chanet, Bruno, Cooper, Lauren D., Courtot, Mélanie, Csösz, Sándor, Cul, Hong, Dahdul, Wasila, Das, Sandip, Dececchi, T. Alexander, Dettal, Agnes, Diogo, Rui, Druzinsky, Robert E., Dumontier, Michel, Franz, Nico M., Friedrich, Frank, Gkoutos, George V., Haendel, Melissa, Harmon, Luke J., Hayamizu, Terry F., He, Yongqun, Hines, Heather M., Ibrahim, Nizar, Jackson, Laura M., Jaiswal, Pankaj, James-Zorn, Christina, Köhler, Sebastian, Lecointre, Guillaume, Lapp, Hilmar, Lawrence, Carolyn J., Le Novère, Nicolas, Lundberg, John G., Macklin, James, Mast, Austin R., Midford, Peter E., Mikó, István, Mungall, Christopher J., Oellrich, Anika, Osumi-Sutherland, David, Parkinson, Helen, Ramírez, Martín J., Richter, Stefan, Robinson, Peter N., Ruttenberg, Alan, Schulz, Katja S., Segerdell, Erik, Seltmann, Katja C., Sharkey, Michael J., Smith, Aaron D., Smith, Barry, Specht, Chelsea D., Squires, R. Burke, Thacker, Robert W., Thessen, Anne, Fernandez-Triana, Jose, Vihinen, Mauno, Vize, Peter D., Vogt, Lars, Wall, Christine E., Walls, Ramona L., Westerfeld, Monte, Wharton, Robert A., Wirkner, Christian S., Woolley, James B., Yoder, Matthew J., Zorn, Aaron M., and Mabee, Paula
Abstract:: Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across...
Resource Type:: Article
Full Text:: flow transport. Bioinspir Biomim 8: 026004. 5. Salmon AB, Leonard S, Masamsetti V, Pierce A

ScholarsArchive@OSU

Myosin-Powered Membrane Compartment Drives Cytoplasmic Streaming, Cell Expansion and Plant Development

Targeting an Essential GTPase Obg for the Development of Broad-Spectrum Antibiotics

High resolution lake sediment record reveals self-organized criticality in erosion processes regulated by internal feedbacks

Swing-Leg Trajectory of Running Guinea Fowl Suggests Task-Level Priority of Force Regulation Rather than Disturbance Rejection

Scaling up sustainability in commodity agriculture: Transferability of governance mechanisms across the coffee and cattle sectors in Brazil

Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon

Finding Our Way through Phenotypes

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