BACKGROUND: This investigation sought to elucidate the relationship between hepatocyte growth factor (HGF)–induced metastatic behavior and the tyrosine kinase inhibitors (TKIs) crizotinib and dasatinib in canine osteosarcoma (OS). Preliminary evidence of an apparent clinical benefit from adjuvant therapy with dasatinib in four dogs is described. METHODS: The inhibitors were assessed...
Environmental DNA (eDNA) is an emerging biological monitoring tool that can aid in assessing the effects of forestry and forest manufacturing activities on biota. Monitoring taxa across broad spatial and temporal scales is necessary to ensure forest management and forest manufacturing activities meet their environmental goals of maintaining biodiversity. Our...
Subhorizontal lake shorelines allow a geodynamic test of the size and extent of a hypothesized paleolake in central Tibet, the East Qiangtang Lake (EQL), during the last interglacial period (marine isotope stage (MIS) 5e). Reconstructions based on relict lake deposits suggest that the EQL would have been ~400 m deep...
The sweet potato is one of the world’s most widely consumed crops, yet its evolutionary history is poorly understood. In this paper, we present a comprehensive phylogenetic study of all species closely related to the sweet potato and address several questions pertaining to the sweet potato that remained unanswered. Our...
Since the early 1900s, widespread agricultural abandonment has occurred in western New York leading to a general increase in forested areas through old-field succession. Even-aged stands typically follow these large-scale disturbances, resulting in a pattern of development with identifiable stages (Oliver 1980). At each stage, changes in vegetation dynamics encourage...
Coastal wetland plants are adapted to varying degrees of inundation. However, functional relationships between inundation and productivity are poorly characterized for most species. Determining species-specific tolerances to inundation is necessary to evaluate sea-level rise (SLR) effects on future marsh plant community composition, quantify organic matter inputs to marsh accretion, and...
Mohonk Preserve intends to manage their forestland more actively with the mission of promoting forest health, climate-adaptation, and overall ecosystem health for the benefit of their community and recreational users. Climate-adaptive management recommendations (recommendations that address climate change vulnerabilities —by promoting either resistance, resilience, or transition— while helping to meet...
Concentrated solar power (CSP) plants have the potential to provide 24 h, renewable electricity. Current CSP systems have high capital and operational costs which makes the levelized cost of electricity uncompetitive with conventional techniques. Recent experimental research has shown the potential of small unit cells (up to 2 × 2 cm) containing micropin arrays...
Supercritical carbon dioxide (sCO2) experiences a drastic change in its thermophysical properties near the thermodynamic critical point. A non-linear thermophysical property variation can influence the heat transfer behavior of sCO2 which is not predicted well by conventional single phase heat transfer theory. This can become a major hindrance in the...