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Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors

Creator:

Pichler, Werner J., Adam, Jacqueline, Watkins, Stephen, Wuillemin, Natascha, Yun, James, and Yerly, Daniel

Abstract:

Small chemicals like drugs tend to bind to proteins via noncovalent bonds, e.g. hydrogen bonds, salt bridges or electrostatic interactions. Some chemicals interact with other molecules than the actual target ligand, representing so-called ‘off-target' activities of drugs. Such interactions are a main cause of adverse side effects to drugs and...

Resource Type:

Article

Full Text:

–541. 27 Yang CW, Hung SI, Juo CG, Lin YP, Fang WH, Lu IH, Chen ST, Chen YT: HLA-B * 1502 bound
Efficient Fabrication of Nanoporous Si and Si/Ge Enabled by a Heat Scavenger in Magnesiothermic Reactions

Creator:

Luo, Wei, Wang, Xingfeng, Meyers, Colin, Wannenmacher, Nick, Sirisaksoontorn, Weekit, Lerner, Michael M., and Ji, Xiulei

Abstract:

Magnesiothermic reduction can directly convert SiO₂ into Si nanostructures. Despite intense efforts, efficient fabrication of highly nanoporous silicon by Mg still remains a significant challenge due to the exothermic reaction nature. By employing table salt (NaCl) as a heat scavenger for the magnesiothermic reduction, we demonstrate an effective route to...

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Article

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(2008). 8. Chen, D. et al. Reversible lithium-ion storage in silver-treated nanoscale hollow porous
Sino-U.S. Agricultural Education

Creator:

Oregon State University. Agricultural Experiment Station

Resource Type:

Technical Report