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Filtering by: Creator Oliveira, Leandro G. License Attribution-NonCommercial-NoDerivs 3.0 United States

Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors

Creator:

Pichler, Werner J., Adam, Jacqueline, Watkins, Stephen, Wuillemin, Natascha, Yun, James, and Yerly, Daniel

Abstract:

Small chemicals like drugs tend to bind to proteins via noncovalent bonds, e.g. hydrogen bonds, salt bridges or electrostatic interactions. Some chemicals interact with other molecules than the actual target ligand, representing so-called ‘off-target' activities of drugs. Such interactions are a main cause of adverse side effects to drugs and...

Resource Type:

Article

Full Text:

with a human G-protein-coupled receptor, MRGPRX2, on mast cells and lead to IgE-independent mast cell
2011/2012 Annual Report

Creator:

Hatfield Marine Science Center

Abstract:

Report year ends June 30.

Resource Type:

Other
2010/2011 Annual Report

Creator:

Hatfield Marine Science Center

Abstract:

Report year ends June 30

Resource Type:

Other