Small chemicals like drugs tend to bind to proteins via noncovalent bonds, e.g. hydrogen bonds, salt bridges or electrostatic interactions. Some chemicals interact with other molecules than the actual target ligand, representing so-called ‘off-target' activities of drugs. Such interactions are a main cause of adverse side effects to drugs and...
We quantified the patterns in macroinvertebrate assemblages and their
associated environmental gradients from 457 least-disturbed wadeable
stream sites across the 48 contiguous United States sampled as part
of US EPA’s National Wadeable Stream Assessment. The majority of the
variation in assemblage composition at the finest taxonomic resolution
was related to...
What affects the oceans affects terra firma. Ocean Solutions, Earth Solutions gathers the insights of more than 50 ocean and coastal science researchers exploring ocean components and their relationships, patterns, and trends over time and space. The book's 16 chapters feature geographic information system (GIS) best practices and include additional...