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Filtering by: Has journal Journal of Alloys and Compounds License Attribution-NonCommercial-ShareAlike 4.0 (CC BY-NC-SA 4.0) Non-Academic Affiliation Oregon State University. Bioresource Research

Detection and Identification of Acetaminophen (Tylenol) Metabolites using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS/MS) Analysis

Creator:

Sanchez, Karina M.

Abstract:

Acetaminophen (APAP) is a commonly used analgesic and antipyretic drug that can cause liver injury, liver necrosis, and liver failure. APAP-induced liver failure (AILF) is associated with depletion of glutathione and the increased formation of APAP protein adducts from the toxic NAPQI metabolite. There is a hypothesized detoxifying pathway where...

Resource Type:

Undergraduate Thesis

Full Text:

each compound to further aid in the identification. We focused on the identification of compounds

ScholarsArchive@OSU

Detection and Identification of Acetaminophen (Tylenol) Metabolites using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS/MS) Analysis

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