Index Catalog // ScholarsArchive@OSU

Creator:: Bouranis, John A.
Abstract:: Phytochemicals from cruciferous vegetables, such as broccoli, contain a multitude of bioactive compounds that prevent and suppress cancer and promote optimal health. Some of the health promoting effects of cruciferous vegetables are attributed to a class of compounds known as isothiocyanates (ITCs), a potent nuclear factor erythroid 2–related factor 2...
Resource Type:: Dissertation
Full Text:: Head of the School of Biological and Population Health Sciences Dean of the Graduate School

Creator:: Lytle, Kelli A., Depner, Christopher M., Wong, Carmen P., and Jump, Donald B.
Abstract:: DHA (22:6,ω3), but not EPA (20:5,ω3), attenuates Western diet (WD)-induced hepatic fibrosis in a Ldlr[superscript −/−] mouse model of nonalcoholic steatohepatitis. We examined the molecular basis for the differential effect of dietary EPA and DHA on WD-induced hepatic fibrosis. DHA was more effective than EPA at preventing WD-induced effects on...
Resource Type:: Article

Creator:: Lytle, Kelli A. and Jump, Donald B.
Abstract:: Background: Nonalcoholic fatty liver disease (NAFLD) is a major public health burden in western societies. The progressive form of NAFLD, nonalcoholic steatohepatitis (NASH), is characterized by hepatosteatosis, inflammation, oxidative stress, and hepatic damage that can progress to fibrosis and cirrhosis; risk factors for hepatocellular carcinoma. Given the scope of NASH,...
Resource Type:: Article
Full Text:: Reversible? Kelli A. Lytle1,2, Donald B. Jump1,2* 1 Nutrition Program, School of Biological and Population

Creator:: Wong, Carmen P., Hsu, Anna, Buchanan, Alex, Palomera-Sanchez, Zoraya, Beaver, Laura M., Houseman, E. Andres, Williams, David E., Dashwood, Roderick H., and Ho, Emily
Abstract:: Epigenetic changes, including aberrant DNA methylation, result in altered gene expression and play an important role in carcinogenesis. Phytochemicals such as sulforaphane (SFN) and 3,3′-diindolylmethane (DIM) are promising chemopreventive agents for the treatment of prostate cancer. Both have been shown to induce re-expression of genes, including tumor suppressor genes silenced...
Resource Type:: Article

Creator:: Miller, Galen W., Ulatowski, Lynn, Labut, Edwin M., Lebold, Katie M., Manor, Danny, Atkinson, Jeffrey, Barton, Carrie L., Tanguay, Robert L., and Traber, Maret G.
Abstract:: The hepatic α-tocopherol transfer protein (TTP) is required for optimal α-tocopherol bioavailability in humans; mutations in the human TTPA gene result in the heritable disorder ataxia with vitamin E deficiency (AVED, OMIM #277460). TTP is also expressed in mammalian uterine and placental cells and in the human embryonic yolk-sac, underscoring...
Resource Type:: Article
Full Text:: America, 3 School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon

ScholarsArchive@OSU