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Creator:: Paraiso, Ines L.
Abstract:: Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...
Resource Type:: Dissertation
Full Text:: synthesis by reducing CYP7A1 expression via SHP, 2) decreases PCSK9 expression, thereby inducing LDL-R

Creator:: Legette, LeeCole L., Luna, Arlyn Y. Moreno, Reed, Ralph L., Miranda, Cristobal L., Bobe, Gerd, Proteau, Rosita R., and Stevens, Jan F.
Abstract:: Obesity contributes to increased risk for several chronic diseases including cardiovascular disease and type 2 diabetes. Xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), was tested for efficacy on biomarkers of metabolic syndrome in 4 week old Zucker fa/fa rats, a rodent model of obesity. Rats received daily oral doses...
Resource Type:: Article
Full Text:: , Ralph L. Reed 1,3 , Cristobal L. Miranda 1,3 , Gerd Bobe 1,4 , Rosita R. Proteau 3 , Jan F

Creator:: Bouranis, John A.
Abstract:: Phytochemicals from cruciferous vegetables, such as broccoli, contain a multitude of bioactive compounds that prevent and suppress cancer and promote optimal health. Some of the health promoting effects of cruciferous vegetables are attributed to a class of compounds known as isothiocyanates (ITCs), a potent nuclear factor erythroid 2–related factor 2...
Resource Type:: Dissertation

Creator:: Lande, Claire, Rao, Sujaya, Morre, Jeffrey T., Galindo, Gracie, Kirby, Julie, Reardon, Patrick N., Bobe, Gerd, and Stevens, Jan Frederik
Abstract:: Linden (Tilia spp.), a profusely flowering temperate tree that provides bees with vital pollen and nectar, has been associated with bumble bee (Bombus spp.) mortality in Europe and North America. Bee deaths have been attributed, with inadequate evidence, to toxicity from mannose in nectar or starvation due to low nectar...
Resource Type:: Article
Full Text:: ). Metabolites detected by NMR were analyzed in Microsoft Excel 2018 and in R version 3.5.3 (©2019). Prior to

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