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Filtering by: Creator Feely, R. A. Remove constraint Creator: Feely, R. A. Non-Academic Affiliation Oregon State University. Center for Genome Research and Biocomputing Remove constraint Non-Academic Affiliation: Oregon State University. Center for Genome Research and Biocomputing Resource Type Dissertation Remove constraint Resource Type: Dissertation

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  • Transcriptomic approaches for discovering regenerative and developmental regulatory networks in zebrafish

    Creator:
    Garland, Michael A.
    Abstract:
    Zebrafish are capable of fully regenerating organs and tissue such as their caudal fin, which is similar to a human regrowing an arm or a leg. In contrast, most mammals including humans have a greatly reduced capacity for wound healing. The ability of zebrafish to undergo this regenerative process, called...
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    Dissertation
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    their caudal fin, which is similar to a human regrowing an arm or a leg. In contrast, most mammals

  • Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

    Creator:
    Chang, Yvonne
    Abstract:
    The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...
    Resource Type:
    Dissertation
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    Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

  • Comparative Aquatic Toxicology of Pesticides and Plastics Using the Model Estuarine Fish, Inland Silverside

    Creator:
    Hutton, Sara J.
    Abstract:
    Based on current trends both pesticide and plastic production are expected to continue to rise in the coming decade. A growing global population coupled with the effects of climate change are the main drivers of increased pesticide use. Throughout this dissertation pesticides refer to herbicides, fungicides, and insecticides. Plastic production...
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    Dissertation
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    expected to continue to rise in the coming decade. A growing global population coupled with the effects

  • Transcriptomic Analyses of Crop Plants using Next-Generation Sequencing Technology

    Creator:
    Geniza, Matthew J.
    Abstract:
    Advancements in molecular biology and computer science have enabled researchers the ability to investigate the transcriptome – the quantification of an organism’s RNA transcripts in response to its environment on a system wide scale. The collective chapters of this thesis utilize high-throughput RNA sequencing, which produces hundreds of millions of...
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    Dissertation
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    Terabytes of RAM. The CGRB cluster takes input from a command-line interface, hosting both Unix and R

  • Investigating Transcriptional Control of Specialized Gene Expression in Plants

    Creator:
    Fraser, Valerie N.
    Abstract:
    Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...
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    Dissertation
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    . Filichkin, Maria G. Ivanchenko, Zachary A. Bright, Russell A. Gould, Olivia R. Ozguc, Shawn T. O’Neil

  • Comparative Transcriptomics in Stress-Induced Rice

    Creator:
    Al-Bader, Noor M.
    Abstract:
    Rice is an important crop that feeds almost half the world population. As climate change models predict floods, drought and extreme temperatures in rice production areas, the need to better understand the genetic basis of adaptation and tolerance to abiotic and biotic stresses is vital to sustain our food supply....
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    Dissertation
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    our food supply. To elucidate stress-tolerance casual genes, we designed a time-series transcriptome

  • Investigating Protein-lipid-membrane Interactions in Plant Cells using Bimolecular Fluorescence Complementation

    Creator:
    Tao, Kai
    Abstract:
    The overall focus of this thesis is on the distribution of specific lipids and membrane proteins of the external and internal membranes of plant cells, in the context of the roles that those lipids and proteins may play in microbe-plant interactions. The work includes the development of several new tools,...
    Resource Type:
    Dissertation
    Full Text:
    chapters. In Chapter 1, I would like to step back to have a general overview, including initial questions