Index Catalog // ScholarsArchive@OSU

Determination of ethyl glucuronide and ethyl sulfate as human biomarkers of alcohol exposure in urine by liquid chromatography/electrospray tandem mass spectrometry with large volume injection

Creator:: Hu, Yan
Abstract:: This research was undertaken to develop a sensitive, selective, and rapid analytical method to measure ethyl glucuronide (EtG) and ethyl sulfate (EtS) in urine as urinary biomarkers of alcohol exposure. Large-volume injection (LVI) coupled with liquid chromatography / electrospray tandem mass spectrometry was used to eliminate the need for either...
Resource Type:: Masters Thesis
Full Text:: . Claudia Maier, and Dr. Fredrick Prahl, for their advice on the dissertation content throughout the

Development of materials and devices for separation of polyamido[a]mine dendrimers

Creator:: Tennico, Yolanda H.
Abstract:: Over the last decade, the use of highly branched macromolecules, called dendrimers, is emerging. Polyamidoamine (PAMAM) dendrimers, in particular, have attracted high interest due to their unique properties, such as well-defined size, shape, and solubility in water. Our group, as part of an interdisciplinary team, is currently working on developing...
Resource Type:: Masters Thesis

Classifying polycyclic aromatic hydrocarbon bioactivities using phenotypic screening and transcriptomics in the developmental zebrafish model

Creator:: Geier, Mitra Celestine
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants that occur in complex mixtures. These environmental mixtures can consist of both parent PAHs and their derivatives. Several parent PAHs are known or suspected mutagens and/or carcinogens, and a handful of PAH derivatives are known to be more potent mutagens and/or carcinogens...
Resource Type:: Dissertation
Full Text:: . William Stubblefield, Dr. Molly Kile, and Dr. Claudia Maier for their guidance and support. I would

Transcriptional networks controlled by the fatty acid regulators FAR-1 and FAR-2

Creator:: Bredeweg, Erin L.
Abstract:: Fungi are capable of growth on a wide variety of carbon sources, both living and dead. They can produce an arsenal of enzymes and transporters for harvesting sugars, polysaccharides, amino acids, lipids and micronutrients from their environments [1]. Within the nucleus of a cell, transcription factors (TF) control whether genes...
Resource Type:: Dissertation
Full Text:: ! Fowler,!Dr.!Claudia!Maier,!and!Dr.!Christine!Kelly!for!their!time!and!input!during!the! process!of

CoLocalized Excitation Emission Resolution : A CLEER approach for multicolor fluorescence analysis

Creator:: Almlie, C. Kyle
Abstract:: Fluorescence has proven to be a robust and powerful method of analysis in numerous fields: forensics, pharmaceutics, geology, food science, and environmental sciences have all developed a large collection of fluorescence instruments and methods to overcome application-specific challenges. Biological applications saw the same development of a fluorescence toolkit with methods...
Resource Type:: Dissertation

Use of Targeted and Non-Targeted Analysis to Study Complex PAH Environmental Mixtures

Creator:: Chibwe, Leah
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous contaminants formed from the incomplete combustion of organic material. These contaminants are of concern because of their widespread presence in the environment and toxic properties. In addition, PAHs encompass a class of diverse compounds with varying physicochemical properties and exist in the environment as...
Resource Type:: Dissertation
Full Text:: additionally thank the members of my graduate committee, Drs. David McIntyre, Claudia Maier, Neal Sleszynski

Poly- and perfluorinated alkyl substance release from landfills and landfill model reactors

Creator:: Allred, Brent McKay
Abstract:: Research and public concern of poly and perfluoroalkyl substances (PFASs) as environmental contaminants has increased significantly due to the increasing number of reports of their detection in humans and wildlife. PFASs have a number of commercial applications including surfactants, coatings, polymers, and levelers, which are used on consumer products like...
Resource Type:: Dissertation
Full Text:: , Dr. Claudia Maier, and Dr. Joseph McGuire. ix CONTRIBUTION OF AUTHORS

Human exposure to polycyclic aromatic hydrocarbons : global cancer risk and metabolism

Creator:: Motorykin, Oleksii
Abstract:: In recent decades, there has been increased attention on human exposure to, and subsequently toxicity of, Polycyclic Aromatic Hydrocarbons (PAHs). PAHs are widespread organic pollutants and some have been shown to be toxic, carcinogenic and mutagenic. This research was focused on understanding the link between global PAH emissions and lung...
Resource Type:: Dissertation
Full Text:: committee members, Dr. Jennifer Field, Dr. Claudia Maier and Dr. William Baird, Dr. Victor Hsu and Dr

Molecular origins of peptide entrapment in polyethylene oxide layers

Creator:: Wu, Xiangming
Abstract:: A more quantitative understanding of peptide entrapment and elution from otherwise protein-repellent polyethylene oxide (PEO) brush layers will provide direction for development of new strategies for drug storage and delivery. Here we describe criteria for peptide integration and structural change within the PEO brush, and discuss the reversibility of peptide...
Resource Type:: Dissertation
Full Text:: McPhail, Dr. Victor Hsu and Dr. Claudia Maier for all the valuable discussion about my research and for

Analytical method development for the identification, detection, and quantification of emerging environmental contaminants in complex matrices

Creator:: Place, Benjamin J.
Abstract:: The development of analytical methods for emerging contaminants creates many unique challenges for analytical chemists. By their nature, emerging contaminants have inherent data gaps related to their environmental occurrence, fate, and impact. This dissertation is a compilation of three studies related to method development for the structural identification of emerging...
Resource Type:: Dissertation
Full Text:: . In addition, I would like to recognize my graduate committee: Dr. Stacey Harper, Dr. Claudia

ScholarsArchive@OSU

Determination of ethyl glucuronide and ethyl sulfate as human biomarkers of alcohol exposure in urine by liquid chromatography/electrospray tandem mass spectrometry with large volume injection

Development of materials and devices for separation of polyamido[a]mine dendrimers

Classifying polycyclic aromatic hydrocarbon bioactivities using phenotypic screening and transcriptomics in the developmental zebrafish model

Transcriptional networks controlled by the fatty acid regulators FAR-1 and FAR-2

CoLocalized Excitation Emission Resolution : A CLEER approach for multicolor fluorescence analysis

Use of Targeted and Non-Targeted Analysis to Study Complex PAH Environmental Mixtures

Poly- and perfluorinated alkyl substance release from landfills and landfill model reactors

Human exposure to polycyclic aromatic hydrocarbons : global cancer risk and metabolism

Molecular origins of peptide entrapment in polyethylene oxide layers

Analytical method development for the identification, detection, and quantification of emerging environmental contaminants in complex matrices

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