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Filtering by: Committee Member Ganguli-Indra, Gitali Non-Academic Affiliation Oregon State University. Honors College Peer Reviewed No

Impaired epidermal homeostasis in Bcl11bR3S/R3S homozygous mutant mice

Creator:

Kelly, Avalon G.

Abstract:

BCL11B, also known as CTIP2, is a transcription factor which plays a critical role in the regulation and development of many tissues and organ systems, including the skin. A 2019 study by Goos et. al. uncovered a novel point mutation in BCL11B gene that converted the Arginine(R)-3 residue to a...

Resource Type:

Honors College Thesis

Full Text:

______________________________________________________________________________ Gitali Indra, Committee Member, representing College of Pharmacy
Characterizing the Interaction between BCL11B and TCF-1 transcription factors in the control of the BCL-xL gene

Creator:

Nagra, Alamjit K.

Abstract:

Immature T cells, known as thymocytes, undergo development through successive stages in the thymus and the periphery to become functional mature T cells. These stages are regulated by sequence specific transcription factors (SSTFs). Two such SSTFs, BCL11B and TCF-1, are both known master regulators of thymopoiesis, which is also known...

Resource Type:

Honors College Thesis

Full Text:

_____________________________________________________________________ Gitali Indra, Committee Member, representing Pharmaceutical Sciences
Lipids of the Stratum Corneum as Predictive Biomarkers for the Development of Atopic Dermatitis in a Pediatric Population

Creator:

Sato, William

Abstract:

Atopic Dermatitis (AD) is a widespread skin disorder, affecting some 20% of the world’s population. Though the precise molecular underpinnings are still being understood, changes in lipid composition within the epidermal stratum corneum (SC) layer have been shown to be closely linked with AD. Previous studies have identified several specific...

Resource Type:

Honors College Thesis

Full Text:

: Arup Indra, Mentor, representing Pharmacy Gitali Indra, Committee Member, representing

ScholarsArchive@OSU

Impaired epidermal homeostasis in Bcl11bR3S/R3S homozygous mutant mice

Characterizing the Interaction between BCL11B and TCF-1 transcription factors in the control of the BCL-xL gene

Lipids of the Stratum Corneum as Predictive Biomarkers for the Development of Atopic Dermatitis in a Pediatric Population

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