Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Advisor Dolan, Brian Non-Academic Affiliation Oregon State University. Honors College

Impact of Unfolded Protein Response, USP14, and NEDD8 Inhibitors Upon Antigen Presentation in SaI/Ak and 4T1 Tumor Cell Lines

Creator:

Godil, Jamila A.

Abstract:

Antigen presentation is a mechanism used by cells to present peptides on the cell surface. Peptides, derived from both viral or self-proteins are presented on the cell surface by MHC Class I molecules to be recognized and detected by cytotoxic T cells. T cells comprise the defense system to protect...

Resource Type:

Honors College Thesis

Full Text:

:_____________________________________________________ Brian Dolan Antigen presentation is a mechanism used by cells to present peptides on the
Cytokine expression in Danio rerio (zebrafish) in response to TLR-7 agonist - Imiquimod

Creator:

Paternostro, Kevin Alan

Abstract:

Utilizing Danio rerio (zebrafish) as a model organism has gained popularity recently, however a lack of research into their immune response pathways had led to the discovery of subclinical infections, and has potentially confounded results. We conducted a study to determine the cytokine expression from TLR activation in order to...

Resource Type:

Honors College Thesis

Full Text:

: ______________________________________________________ Brian Dolan Utilizing Danio rerio (zebrafish) as a model organism has gained popularity
Evaluation of a Monoclonal Antibody for Studying MHC Class I Antigen Presentation In-Vitro

Creator:

VanderHoek, Eden N.

Abstract:

Human epidermal growth factor receptor 2 (HER2), a member of the receptor tyrosine kinase (RTK) family, is frequently dysregulated in a variety of cancers. Overexpression of the receptor leads to increased cell proliferation and resistance to cell death due to downstream signaling effects. Proteasomal degradation of HER2 results in the...

Resource Type:

Honors College Thesis

Full Text:

Soheila Kazemi _____________________________________________________ Brian Dolan Human