Index Catalog // ScholarsArchive@OSU

A Nascent Helix in Dynein Intermediate Chain is Essential for Regulating Dynein/Dynactin Complexes

Creator:: Saravanan, Sanjana
Abstract:: Cytoplasmic dynein is a motor protein complex found in eukaryotes that is essential to many cellular processes. With dynein being involved in mitosis, axonal transport and organelle transport, disruption of dynein function can lead to neurodegeneration and other diseases. The main function of dynein is transportation of cargo through the...
Resource Type:: Honors College Thesis
Full Text:: (ITC), circular dichroism (CD) and nuclear magnetic resonance (NMR) are used to map the binding site

Structural and activity characterization of irradiated antimicrobial peptide (WLBU2) for use in blood processing and biomedical applications

Creator:: Cheung, Daniel Y. C.
Abstract:: Sepsis is a life-threatening blood infection which leads to an uncontrolled systemic inflammatory state. In North America alone, sepsis annually afflicts approximately 750,000 individuals and kills 38-50% of these (more than HIV/AIDS, breast cancer, and colon cancer combined). Current treatment involves administration of IV fluids, antibiotics and hemoperfusion, requiring prolonged...
Resource Type:: Honors College Thesis
Full Text:: circular dichroism (CD), and mass spectrometry to characterize chemical and structural changes caused by

Never Man Enough: Aggrieved Entitlement and Weaponized Insecurity in White American Men

Creator:: Sullivan, Riese C.
Abstract:: This paper examines the recent evolution of aggrieved entitlement and social fragility in young white American males and the subsequent violent backlash that certain individuals in this group have unleashed upon women, the LGBTQ community, Jewish people, Black people, and other socially vulnerable populations. Throughout the past decade, America at...
Resource Type:: Honors College Thesis
Full Text:: contribute to toxic, circular “logic” employed by these volatile mindsets. Keywords: Masculinity

Characterization of Fer1L6 in the mouse C2C12 cell line

Creator:: Huegel, Jacob T.
Abstract:: Fer1L6 is an uncharacterized member of the ferlin family of proteins, a group of large, calcium sensitive proteins with emerging roles in vesicle trafficking and various disease states. The presence of Fer1L6 has been identified within the C2C12 cell line of mouse skeletal muscle. To determine the protein’s subcellular location...
Resource Type:: Honors College Thesis
Full Text:: each other their oligonucleotides will ligate together and undergo circular a circular polymerase

Differential Binding and Structural Properties of the WWC Protein Family

Creator:: Rodriguez, Diego Javier
Abstract:: The WWC family consists of three proteins‐ KIBRA/WWC1, WWC2, and WWC3. The three proteins share a similar primary structure and interact with a common set of proteins. Each paralog contains two WW domains which recognize proline‐rich sequences of the type PPxY (P is proline, Y is tyrosine, x is any...
Resource Type:: Honors College Thesis
Full Text:: ............................................................................................ 10 2.5. Circular Dichroism

Design of 3D-Printed Soft Pneunet Actuator for Robotic Fruit Harvesting

Creator:: Wilhelm, Lissette J. H.
Abstract:: This work details the development of 3D printed TPU pneunet actuators for use in apple picking for agricultural soft robotics. These actuators increase the force capabilities of soft pneunets and simplify manufacturing. Grippers based on these actuators are ideal for apple picking because they are compliant, yet exert sufficient force...
Resource Type:: Honors College Thesis
Full Text:: inflated, they form a triangular shape rather than the more circular shape seen in silicone [20]. (a) The

Characterization and application of PEO-containing triblock copolymer surfactants

Creator:: Snider, Joshua L.
Abstract:: The action of pendant, polyethylene oxide (PEO) brush layers as nonfouling coatings for biomedical materials is well understood. However progress toward clinical application of stable, high density PEO coatings has historically been impeded by the lack of cost effective, noninvasive methods for their preparation. Triblock polymers featuring a hydrophobic, polypropylene...
Resource Type:: Honors College Thesis
Full Text:: surfaces by gamma irradiation. J. of Biomedical Materials Research (Vol. 38, pp. 289-302). Zawada, R. J

Characterization of the SARS-CoV-2 Nucleocapsid Protein and the Binding to Different Sections of the SARS-CoV-2 Genome

Creator:: Pinckney, Seth H.
Abstract:: The nucleocapsid protein (N protein) of the severe acute respiratory syndrome coronavirus 2 is known to play an essential part of the virus’ functions. The N protein can protect and package the large 29,903 nucleotide genomic RNA whilst also interacting with structural membrane protein M and the spike protein S....
Resource Type:: Honors College Thesis
Full Text:: ). Circular dichroism Spectra were recorded on a JASCO 720 spectropolarimeter (Jasco, Oklahoma City, OK

Molecular origins of peptide entrapment within polyethylene oxide brush layers

Creator:: Lampi, Marsha C.
Abstract:: Effective surface coatings for tissue-contacting medical devices should prevent both biofilm formation and infection. One method to achieve this aim is protein repellant polyethylene oxide (PEO) brush coatings loaded with antimicrobials. Previous research has demonstrated that the antimicrobial nisin adsorbs to PEO brush layers in multi-layer amounts and suggests that...
Resource Type:: Honors College Thesis
Full Text:: ) immediately prior to all OWLS testing. 14 Peptide structure was evaluated by circular dichroism (CD

Enhanced Delivery of Cryoprotectant Chemicals to Cultured Neurons

Creator:: Wilson, Jenna L.
Abstract:: Due to the many advances in the areas of biotechnology and medicine, the need for long- term storage and stabilization of biological materials is rapidly increasing. The field of biopreservation is attempting to address these issues by finding ways to maintain the integrity and functionality of proteins, cells, and organs...
Resource Type:: Honors College Thesis

ScholarsArchive@OSU

A Nascent Helix in Dynein Intermediate Chain is Essential for Regulating Dynein/Dynactin Complexes

Structural and activity characterization of irradiated antimicrobial peptide (WLBU2) for use in blood processing and biomedical applications

Never Man Enough: Aggrieved Entitlement and Weaponized Insecurity in White American Men

Characterization of Fer1L6 in the mouse C2C12 cell line

Differential Binding and Structural Properties of the WWC Protein Family

Design of 3D-Printed Soft Pneunet Actuator for Robotic Fruit Harvesting

Characterization and application of PEO-containing triblock copolymer surfactants

Characterization of the SARS-CoV-2 Nucleocapsid Protein and the Binding to Different Sections of the SARS-CoV-2 Genome

Molecular origins of peptide entrapment within polyethylene oxide brush layers

Enhanced Delivery of Cryoprotectant Chemicals to Cultured Neurons

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