Mercury exposure is widely common throughout the world, ranging from sources such as dental amalgams, fish and seafood consumption, industrial mining, and medicine. A straightforward, efficient, and affordable protocol to measure urine mercury content would greatly contribute to assessing one’s mercury exposure and in categorizing populations that are more vulnerable...
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Dr. AdrianGombart
Mercury exposure is widely common throughout the world, ranging from sources
The gut microbiome influences human disease including Type 2 diabetes, obesity and metabolic syndrome and interacts with the innate immune system. The human cathelicidin antimicrobial peptide (hCAMP), an important component of the innate immune system, and vitamin D and xanthohumol, a natural compound found in beer hops, regulate its expression....
Vitamin E (vitE) is a group of lipid-soluble antioxidants- of which alpha-tocopherol is the most biologically active and only form considered to be an essential nutrient. Through preferential binding and trafficking, the alpha-tocopherol transfer protein (α-TTP) regulates the concentration of vitE in the body. The impact of vitE deficiency on...
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AdrianGombart, Committee Member, representing Department of Biochemistry and Biophysics
Fiction facilitates the attribution of unrealistic character traits to scientists, and skews general understanding of the scientific process-- a fatal flaw resulting in self-doubt within undergraduate scientists, and apprehension and distrust in several communities. Misconceptions and the absence of significant ideas were identified by analyzing novels within the “Lab Lit”...
Circadian regulation is essential for many physiological functions, from sleep/wake patterns to hormonal rhythms. While the brain’s biological clock, the suprachiasmatic nucleus (SCN), likely plays a role in reproductive rhythms, it remains unknown if intracellular circadian clocks elsewhere contribute to the neuroendocrine control of reproduction. Gonadotropin-releasing hormone (GnRH) stimulates pituitary...
A great deal of research has been focused on the microbiomes of terrestrial angiosperms (flowering plants), but much less research has been performed on the microbiomes of aquatic angiosperms (Turner et al. 2013). Eelgrass beds are extremely productive ecosystems that provide habitat for many marine organisms, such as fish, shellfish,...
Metal Organic Framework Structures (MOFs) have shown great promise for use in gas storage. Computer simulations have been touted as a method to identify strong candidate molecules for experimental research. This project assessed the relationship between computer simulations of methane absorption and experimental gas absorption. We acquired experimental data and...
Sepsis is a life-threatening blood infection which leads to an uncontrolled systemic inflammatory state. In North America alone, sepsis annually afflicts approximately 750,000 individuals and kills 38-50% of these (more than HIV/AIDS, breast cancer, and colon cancer combined). Current treatment involves administration of IV fluids, antibiotics and hemoperfusion, requiring prolonged...
Interest in organizational culture has grown enormously over the last twenty years and much
effort has gone into investigating the relationship between organizational culture and
performance. Because most research to date has focused on large organizations, we chose to
investigate the culture in a community bank undergoing a cultural transformation....
Chlorinated aliphatic hydrocarbons (CAHs) like trichloroethene (TCE) were mostly used to replace drying cleaning fluids which contained hydrocarbons like benzene, and were highly flammable. Through improper disposal, storage, and spills, TCE and its downstream products, like cis-dichloroethene (cDCE) and vinyl chloride (VC), leached into groundwater and threaten human and environmental...