Complex organic transformations, such as the addition of pyrrole to ketene using planar chiral organocatalyst (*PPY), the four-component anhydride- Manniach reactions, and the site-selective desymmetrization of meso-1,2-diol, are remarkable synthetic reactions that provide high yield and high selectivity. However, the exact mechanism and origins of stereocontrol for theses synthetic organic...
This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Urban areas currently cover a small fraction of Oregon’s landscape but will expand to accommodate an increasingly large proportion of the state’s growing population and economic activity. Residential developments on rural lands now cover more than twice the area occupied by Oregon’s urban developments and are growing rapidly. Oregon urban...
The use of an adjacency matrix to determine distant (not maximal or
minimal) subgroup and supergroup relationships between crystallographic spacegroup
types is described. Full lists of space-group types that are supergroups and
subgroups for every space-group type were compiled. A list of the space-group
types connected to each space-group type...
Reliability-based geotechnical foundation design focusses on soil and structure analysis that meets necessary safety, performance and/or serviceability criteria, calibrated based on probabilistic analyses and an accepted level of risk. As the civil engineering community seeks to better harmonize geotechnical and structural design methodologies, reliability-based design is being incorporated more into...