T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
In the problem of testing the median using a random sample from a
certain distribution, and if no other parametric family is suggested,
the t-test is known to be the optimal procedure when this distribution
is normal. If the sample appears to be non-normal, one has the choice
either to...
This is a bibliography of the work of T. L. Jackson, who conducted research at the North Willamette Research and Experiment Center. It is limited to those Extension publications and research reports that addressed the nutrient needs of fresh market and processed vegetables.
Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
A study of populations characteristics of T. turgidum ssp.
carthlicum and T. aestivum ssp. carthlicoides was completed using
numerical analysis. A sample of 74 accessions of ssp. carthlicum
and 20 of ssp. carthlicoides were scored for 46 characters. It was
established that three morphological distinguishable groups of ssp.
carthlicum can...
The first published notion that the j-function was in any way related to the Monster came in 1979, when Conway and Norton noted in [CN79] that each coefficient in the q- expansion of the j-function could be written as a (nontrivial) integral linear combination of the dimensions of irreducible representations...
In this paper, an analysis of the clock-feedthrough effects in
switched-current (SI)' circuits will be presented. The clock-feedthrough
effects caused by the non-ideal characteristic of MOS
switches when they are turned off limit the accuracy of the analog
track-and-hold (T/H) circuits. A model to analyze and characterize this
effect is...
This thesis traces the relationship between the First World War, constructions of masculinity, and the life and poetry of T.S. Eliot. Central to this relationship is a study of homoeroticism, which the author characterizes as different from homosexuality but not exclusive of it, in late 19th and early 20th century...
Ten T-mycoplasma strains isolated from the urine of male
students with nongonococcal urethritis were compared in immunodiffusion,
indirect hemagglutination (IHA), metabolic inhibition (MI),
and immunoelectrophoretic tests using antigens prepared from these
isolates and specific rabbit antisera. Immunodiffusion, MI, and IHA
tests revealed complex antigenic interrelationships among the
T-mycoplasmas, whereas immunoelectrophoretic...
A study of the relative rates of the alkyl hydrogen abstraction
from a series of meta and para substituted t-butylbenzenes by the
chlorine atom at 70°C has been carried out. Application of the
Hammett equation yielded a ρ value of -0.44 for the para compounds.
Possible explanations for the non-linearity...
The spectrophotometric titration of the tyrosine residues,
their reaction with N-acetylimidazole, and the effect of pH on the
thermally induced conformational transition of ribonuclease T₁ have
been investigated. The results of spectrophotometric titration in
0.20 M KCl/0.001 M sodium phosphate suggest that titration of the
tyrosine residues occurs in two...
The purpose of this study was to determine if
students' school-related attitudes are significantly
affected by teacher classroom discipline management based
upon concepts contained in Judicious Discipline: A Constitutional
Perspective for School Rules (Gathercoal, 1986).
The data relative to student school-related attitudes
of elementary, middle, and high school students toward...
The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...
Proper immune function is indispensable, as failure to mount an immune response against a pathogen can lead to serious complications or even death. T cells act by enhancing the activation of phagocytic cells as well as the activation of B cells. Their widespread influence on an immune response makes optimal...
This paper examines ways in which natural resource management – NRM – may be decolonized in order to better serve Hawaiʻi communities. Expressed needs for diversity in NRM has brought about inclusion of traditional ecological knowledge in recent years. Here, traditional ecological knowledge is redefined as ʻIK, ʻike kupuna –...
The search for the stand density that optimizes growth and hence generates the maximum amount of wood is one of the philosopher’s stone in modern forestry. Since scientific methods were applied to forestry, numerous generations of foresters have studied the relations between stocking density and growth, obtaining diverse results and...
We have developed crown-gall resistant transgenic plants capable of suppressing Agrobacterium tumefaciens T-DNA oncogenes. Crown gall tumors result from overproduction of auxin and cytokinin in plant cells transformed by A. tumefaciens. High phytohormone levels result from expression of two auxin biosynthetic genes, tryptophan monooxygenase (iaaM) and indole acetamide hydrolase (iaaH),...
This paper describes the synthesis of t-butyl bicyclo[7.1.0]
decane-2-percarboxylate and its photolytic decomposition. The title
compound was found to undergo simple homolytic cleavage when exposed
to light of 2537 A; producing the cyclodecyl radical, carbon dioxide,
and t-butoxy radical. The largest percentage of products arose from
an intimate radical pair...
The research examines the effect of restricted head and neck movement on
driving performance as measured by decision time at T-intersections. The traffic
safety and human factors literature was reviewed, and very little was found
concerning drivers with physical limitations. T-intersections were selected for
study because most accidents involving drivers...
My thesis explores the later work of author J.D. Salinger, including two narratives featured in Nine Stories, "A Perfect Day for Bananafish," and "Teddy," and Franny and Zooey, "Raise High the Roof Beam, Carpenters," and "Seymour: an Introduction." Through my analysis I argue that the religious nature of Salinger's fiction...
This thesis investigated the methods of failure in the webs of
built up girders. The beams had rectangular holes five and one-half
inches wide and seven and one-half inches high with rounded corners
in a web fourteen inches deep between flanges. The longitudinal
position of the hole edge varied from...
Platelets undergo morphological changes essential to hemostasis upon activation at sites of vascular injury. The Rho GTPases Rac1, Cdc42, and RhoA drive these changes. Rho guanine nucleotide dissociation inhibitors (RhoGDIs) bind to the Rho GTPases to block the GDP from dissociating from the Rho GTPases, as well as anchoring the...
This paper investigates a particular bridge construction technique
which could result in a significant torsional moment. The
structural member under consideration is a prestressed concrete
girder for which no torsional consideration is made.
Torsional shear stresses can be adequately approximated for
an I-shaped girder. Laboratory model tests were performed to...
Platelet activation uses a complex set of pathways to respond to vascular injury during hemostasis. However, thrombosis relies on the same set of pathways. Antiplatelet therapies used to prevent thrombotic events often target the P2Y₁₂ platelet receptor for inhibition but can result in bleeding diathesis or in abnormally high ADP...
Two built-up wide-flange beams with several large holes in each
beam were tested to failure. Strains were measured by strain gages
at various levels, located at the ends and center of typical holes, and
deflections were measured optically at two points on each beam.
Lateral bracing was provided to prevent...
This paper investigates the proposed preliminary designs of
two gymnasiums with respect to gamma radiation shielding due to
radioactive fallout. For each building a determination is made of
the protection offered from radiation fallout. If the degree of protection
is below the minimum value set by the Office of Civil...