1-(2-pyridyl)-3-methyl-3-butene-2-ol was prepared by allowing 2-picolyllithium to react with methacrolein.
In the reaction of picolyllithium with crotonaldehyde, two products 1-(2-pyridyl)-4-methyl-3-butene-2-ol and 1-(2-pyridyl)-4-methyl-2-butene-4-ol were formed.
1-(2-pyridyl)-3-methyl-3-butene-2-ol was subjected to the low
pressure hydrogenation, using methanol as solvent and PtO₂ as catalyst. A red yellow liquid 1-(2-pyridyl)-3-methyl-2-butanol was
obtained. Derivatives of the...
The reaction of certain purin-8-ols with phosphorus
oxychloride and N,N-diethylaniline are described.
9-Amino-6-chloropurin-8-ol monohydrate reacted with
phosphorus oxychloride and N, N-diethylaniline to yield
the phosphorus oxychloride adduct. Other purin-8-ols
were prepared and the production of analogs similar to
the previously mentioned adduct was attempted.
6-Chloropurin-8-ol and 6, 9-diaminopurin-8-ol hydrochloride
monohydrate...
Both oxy-Cope and siloxy-Cope rearrangements involve
(1, 3) and (3, 3) sigrnatropic shifts. Both the concerted mechanism,
and the stepwise mechanism via a diradical intermediate are possible.
In a cyclic system such as cis-l-vinylcyclooct-3-en-l-ol, the thermal
rearrangement takes place preferably through a diradical intermediate.
At high temperature, the reaction also...
The thermolysis of trans-1 -trimethylsiloxy- 1-vinylcyclotridec-
3-ene (VI-OTMS) led to the formation of two major products: 4-vinylcyclotridecanone
(VII) and cyclopentadec-5-en-l-one (VIII) after
hydrolysis. Ketone VII is produced by a concerted [3, 3] sigmatropic
shift, while ketone VIII is formed by a [1, 3] sigmatropic shift with
a concerted or diradical...
The thermal and anionic rearrangements of substituted 1-vinyltrans-
cyclotridec-3-en-l-ol compounds have been studied to determine
what effects substituents would have on the sigmatropic shift when
placed on the two positions of the 1-vinyl group.
For the thermal rearrangements, the a-substituted vinyl-trans-cyclotridecenols
gave both the [3,3] and [1,3] shift products of...
E8,E10-dodecadien-1-ol, the primary component of the female sex pheromone of codling moth, Cydia pomonella L., has no attraction to male Oriental fruit moth (OFM), C. molesta (Busck). However, this compound when added to the OFM pheromone blend of Z8-dodecenyl acetate (85.5%), E8-dodecenyl acetate (5.5%), and Z8- dodecen -1 -ol (9.0%),...
Green bean flavor has been studied since the 1960’s to better understand Blue Lake flavor in processed green beans in Oregon. Research by Stevens and colleagues showed that Blue Lake flavor could be reconstituted in a bland bean by adding 0.4ppm of 1-octen-3-ol and 1.6ppm of 3-hexen-1-ol. These two volatile...