This dissertation integrates a process-based hydrological investigation with an
ongoing paired-catchment study to better understand how forest harvest impacts
catchment function at multiple scales. We do this by addressing fundamental questions
related to the stocks, flows and transit times of water. Isotope tracers are used within a
top-down catchment intercomparison...
A disproportionate amount of HIV/AIDS cases each year occur among African Americans. The purpose of this study was to review the numerous studies on HIV/AIDS conspiracy beliefs and their effects into one document. This research was done using research databases to indentify peer-reviewed journal articles on HIV/AIDS conspiracy beliefs, and...
Vaccinia virus (VV) encodes at least six proteins that are modified by the addition of a 14-carbon saturated fatty acid through an amide linkage and at least eight proteins that are modified post-translationally by the addition of a 16-carbon saturated fatty acid through linkage to cysteine residues. These post-translational modifications...
The attachment of myristic acid to the N-terminal glycine residue of many
eukaryotic and viral proteins is often essential for the acquisition of the protein's
biological activity. Vaccinia virus (VV), the prototype member of the Poxviridae,
expresses several myristylated proteins during the course of infection. Only one of
these proteins,...
Vaccinia virus-infected animal cells have been used to
study the interactions between the replication of
deoxyribonucleic acid (DNA) and the biosynthesis of its
nucleotide precursors. Some antimetabolites that inhibit
DNA replication have as their targets enzymes of nucleotide
biosynthesis. Furthermore, the disruption of nucleotide
metabolism can alter the fidelity of...
Imbalanced deoxyribonucleoside triphosphate (dNTP) pools are mutagenic for DNA synthesis in both intact cells and cell-free replication systems. Almost certainly, such mutagenesis involves competition between correctly and incorrectly base-paired precursors at replication sites. However, there are certain differences between the intact cell and cell-free systems that do not always allow...
Irrigated agriculture constitutes the greatest consumptive water use globally, so that irrigation efficiency measures are an important part of global efforts to best utilize this limited resource. However, greater irrigation efficiency must be achieved while simultaneously maintaining or increasing crop yields and farming profitability. Incremental water use decisions are made...
A synthesis of over 2000 paleoclimate proxy records is performed via a data assimilation framework that expands upon previous efforts by implementing a suite of physically-based proxy system models, and which provides the first example of an observationally independent, multi-seasonal (DJFM, JJAS) paleoclimate reanalysis. This methodology is contrasted against previous...
Data science is a rapidly growing industry permeating throughout every aspect of society. Everything collects data these days, and people use this data to find meaningful patterns leading to benefits ranging from more intuitive marketing to better cancer detection. However, increased data collection also leads to increased complexity, and data...
After the commercial exploitation of humpback whales (Megaptera Novaeangliae) ceased, population trends in the North Pacific increased with the implementation of federal protective legislation. The recovery of the population prompted the National Oceanic and Atmospheric Administration to divide the population into 14 Distinct Population Segments (DPSs) based on discrete geographic...