T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
The spectrophotometric titration of the tyrosine residues,
their reaction with N-acetylimidazole, and the effect of pH on the
thermally induced conformational transition of ribonuclease T₁ have
been investigated. The results of spectrophotometric titration in
0.20 M KCl/0.001 M sodium phosphate suggest that titration of the
tyrosine residues occurs in two...
The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
The effect of dietary glycosylated vitamin B-6 on the bioavailability
of vitamin B-6 was determined in 4 women. A 44-d metabolic-balance diet
study was divided into a preliminary 8-d adjustment period followed by
two 18-d experimental periods. The subjects were divided into two groups
in a crossover design to compare...
In two studies we tested the effect of vitamin B-6
(B-6) intake on in vitro lymphocyte, proliferation and IL-2
production in healthy young women. In Study I, 6 women were
fed a constant diet containing 0.84 mg (4.96 μmols) of B-6
for 12 d, and 1.24 mg (7.33 μmols) and...
The objective of this research was to indirectly determine the
existence of a possible retinal-endocrine pathway activated, or
Inhibited, by artificial fluorescent light as evidenced by it subsequent
effects on bone metabolism. Forty-eight male Long-Evans post-breeder
rats, half of which were bilaterally orbitally enucleated, were
used in this experiment. A...