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Creator:: Mohamed, Osama H.
Abstract:: This dissertation describes how to apply pharmacokinetic simulations and modeling in a clinical setting to monitor and adjust drug dosing in special patient populations. Pharmacokinetic simulations were used to investigate efficacy and risk of drug toxicity of a new dosing regimen for aminoglycoside antibiotics when administered to renal failure patients....
Resource Type:: Dissertation

Creator:: Singh, Amandip
Abstract:: Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium that is capable of causing infections in people who are immune compromised. The bacterium can live in a variety of environments due to the variety of virulence factors it can produce. It is well adapted to living in iron-stringent conditions because it can...
Resource Type:: Honors College Thesis
Full Text:: , pyocin, evolution Corresponding e-mail address: singha@oregonstate.edu 2

Creator:: Glover, Rochelle
Abstract:: When iron levels are low, the opportunistic pathogen Pseudomonas aeruginosa secretes the high-affinity iron-binding siderophore pyoverdine. The cognate ferripyoverdine receptor, FpvA, has gained attention as the most divergent gene in the organism’s genome, showing substantial evidence of positive selection. S-type pyocins, bacteriocins with specificity to Pseudomonads, enter cells through FpvA...
Resource Type:: Honors College Thesis
Full Text:: Key Words: Pseudomonas aeruginosa, pyoverdine, pyocin, evolution, expression Corresponding e-mail

Creator:: Miller, Suzanne C. McKenzie
Abstract:: Burkholderia cepacia complex (Bcc) bacteria reside in soil, plant rhizospheres, and water, but the prevalence of Bcc in outdoor environments is not clear. In this study, we sampled a variety of soil and rhizosphere environments with which people may have contact: playgrounds, athletic fields, parks, hiking trails, residential yards and...
Resource Type:: Masters Thesis
Full Text:: found to induce the inflammatory marker tumor necrosis factor c (TNF-a) to levels achieved by E. coli

ScholarsArchive@OSU