The mixed electronic and ionic conductivity of perovskite oxides has enabled their use in diverse applications such as automotive exhaust catalysts, solid oxide fuel cell cathodes, and visible light photocatalysts. The redox chemistry at the surface of perovskite oxides is largely dependent on the oxidation state of the metal cations...
Dendrimers are well-defined, polymeric nanomaterials currently being investigated for biomedical applications such as medical imaging, gene therapy, and tissue targeted therapy. Initially, higher generation (size) dendrimers were of interest because of their drug carrying capacity. However, increased generation was associated with increased toxicity. The majority of studies exploring dendrimer toxicity...
Experiments were conducted to determine survival, growth, and accumulation of HEOD (major component of dieldrin) in the tissues of steelhead trout (Salmo gairdneri) embryos, alevins, and fry exposed to dieldrin concentrations ranging from 0.012 to 52 ppb. The fish were held in specially designed exposure chambers provided with continuously renewed...
Firemaster 550 (FM550) is an additive flame retardant mixture used within polyurethane foam and is increasingly found in house dust and the environment due to leaching. Despite the widespread use of FM550, very few studies have investigated the potential toxicity of its ingredients during early vertebrate development. In the current...
The study of the effects of diethyldithiocarbamate (DEDTC) in some diseases is in focus for many years. However, DEDTC is a metal chelator that can present neurotoxicity as side effects. Here we investigate the effect of DEDTC on brain Zinc (Zn) content and behavior. To address this issue we used...
Soluble butane monooxygenase (sBMO), a three-component di-iron monooxygenase complex
expressed by the C2–C9 alkane-utilizing bacterium Thauera butanivorans, was kinetically
characterized by measuring substrate specificities for C1–C5 alkanes and product inhibition
profiles. sBMO has high sequence homology with soluble methane monooxygenase (sMMO) and
shares a similar substrate range, including gaseous and...
Bisphenol A (BPA), a high-volume chemical used to make polycarbonate plastic and epoxy resins, is a ubiquitous contaminant in environment and human body. To investigate the reproductive effects of long-term exposure to low concentrations of BPA, a two-generation study was conducted using the aquatic model species of zebrafish. Our findings...
Rangelands are significant providers of ecosystem services in agroecosystems world‐wide. Yet few studies have investigated how different intensities of livestock grazing impact one important provider of these ecosystem services—native bees. We conducted the first large‐scale manipulative study on the effect of a gradient of livestock grazing intensities on native bees...
In this article we consider the current educational needs for science and policy in marine resource management, and we propose a way to address them. The existing literature on cross-disciplinary education in response to pressing environmental problems is vast, particularly in conservation biology. However, actual changes in doctoral-level marine science...
Development of herbicide-resistant crops has resulted in significant changes to agronomic practices, one of which is the adoption of effective, simple, low-risk, crop-production systems with less dependency on tillage and lower energy requirements. Overall, the changes have had a positive environmental effect by reducing soil erosion, the fuel use for...
Laboratory-based testing does not allow for the sufficiently rapid return of data to enable optimal therapeutic monitoring of patients with metabolic diseases such as phenylketonuria (PKU). The typical turn-around time of several days for current laboratory-based testing is too slow to be practically useful for effective monitoring or optimizing therapy....
Carbonyl sulfide (COS) has been investigated as a rapid-equilibrium inhibitor of CO oxidation
by the CO dehydrogenase purified from Rhodospirillum rubrum. The kinetic evidence suggests that the
inhibition by COS is largely competitive versus CO (Ki = 2.3 pM) and uncompetitive versus methylviologen
as electron acceptor (Ki = 15.8 pM)....
BACKGROUND: Predictive modeling of the biological effects of nanomaterials is critical for industry and policymakers to assess the potential hazards resulting from the application of engineered nanomaterials.
METHODS: We generated an experimental dataset on the toxic effects experienced by embryonic zebrafish due to exposure to nanomaterials. Several nanomaterials were studied,...
Spatial variation of available food resources can be difficult to accurately quantify for wide ranging organisms
at landscape scales. Lichens with usnic acid, a yellowish pigment, constitute a large portion of caribou winter
diet across much of their range. We take a new approach of modeling lichen abundances by capitalizing...
Ammonia (NH₃)-oxidizing bacteria (AOB) and thaumarchaea (AOA) co-occupy most soils, yet no short-term growth-independent method exists to determine their relative contributions to nitrification in situ. Microbial monooxygenases differ in their vulnerability to inactivation by aliphatic n-alkynes, and we found that NH₃ oxidation by the marine thaumarchaeon Nitrosopumilus maritimus was unaffected...
Rivers display temporal dependence in suspended sediment–water discharge relationships. Although most work has focused on multi-decadal trends, river sediment behavior often displays sub-decadal scale fluctuations that have received little attention. The objectives of this study were to identify inter-annual to decadal scale fluctuations in the suspended sediment–discharge relationship of a...