Potentially relevant literature for the years 1990-1999 was identified by (a) conducting keyword searches of computerized bibliographic databases, especially CAB Abstracts and Aquatic Sciences and Fisheries Abstracts, (b) reading through the tables of contents of a few especially relevant journals, (c) searching the internet for pertinent bibliographies, and (d) to...
Novel broad-spectrum antimicrobials are a critical component of a strategy for combating antibiotic-resistant pathogens. In this
study, we explored the activity of the broad-spectrum antiviral compound ST-669 for activity against different intracellular bacteria
and began a characterization of its mechanism of antimicrobial action. ST-669 inhibits the growth of three different...
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as
B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity
of morpholino phosphorodiamidate oligomers (PMOs) in dystrophin-deficient mdx mice. In the present study, the general
mechanistic significance of the...