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Identification of Novel Gammaherpesviruses in Ocelots (Leopardus pardalis) and Bobcats (Lynx rufus) in Panama and Colorado, USA

Creator:

Lozano, Caitlin C., Sweanor, Linda L., Wilson-Henjum, Grete, Kays, Roland W., Moreno, Ricardo, VandeWoude, Sue, and Troyer, Ryan M.

Abstract:

Gammaherpesviruses (GHVs) have been identified in many species and are often associated with disease. Recently, we characterized three novel felid GHVs in domestic cats, bobcats, and pumas. In this study we sought to determine whether free ranging ocelots (Leopardus pardalis) and bobcats (Lynx rufus) are infected with additional GHVs. We...

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Article

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gammaherpesviruses in ocelots (Leopardus pardalis) and bobcats 1 (Lynx rufus) 2 Caitlin C. Lozano,1 Linda L
Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit Expression

Creator:

Saldivar, Joshua C., Miuma, Satoshi, Bene, Jessica, Hosseini, Seyed Ali, Shibata, Hidetaka, Sun, Jin, Wheeler, Linda J., Mathews, Christopher K., and Huebner, Kay

Abstract:

Genomic instability drives tumorigenesis, but how it is initiated in sporadic neoplasias is unknown. In early preneoplasias, alterations at chromosome fragile sites arise due to DNA replication stress. A frequent, perhaps earliest, genetic alteration in preneoplasias is deletion within the fragile FRA3B/FHIT locus, leading to loss of Fhit protein expression....

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Article

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, Seyed Ali Hosseini2, Hidetaka Shibata2¤, Jin Sun2, Linda J. Wheeler3, Christopher K. Mathews3, Kay

ScholarsArchive@OSU

Identification of Novel Gammaherpesviruses in Ocelots (Leopardus pardalis) and Bobcats (Lynx rufus) in Panama and Colorado, USA

Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit Expression

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