Active mountain building associated with the accretion of the Yakutat microplate (YT) in southern Alaska is characterized through the combination of a new balanced cross section and new low-temperature cooling ages. This analysis constrains the amount and timing of shortening, the spatial and temporal trends of exhumation, and the interplay...
A major achievement in research supported by the Kluane Lake Research Station was the recovery, in 2001–02, of a suite of cores from the icefields of the central St. Elias Mountains, Yukon, by teams of researchers from Canada, the United States, and Japan. This project led to the development of...
Western diets are high in fat and sucrose and can influence behavior and gut microbiota. There is growing evidence that altering the microbiome can influence the brain and behavior. This study was designed to determine whether diet-induced changes in the gut microbiota could contribute to alterations in anxiety, memory or...
This scanned article is provided to correct an error on the publisher’s website. The online version has incorrectly given the first author name as “Listen, Aaron” rather than the correct, “Liston, Aaron.” If using this article, please cite the first author correctly.
The protein palmitoylation cycle has been shown to be important for protein signaling and synaptic plasticity. Data from our lab showed a change in the palmitoylation status of certain proteins with age. A greater percentage of the NMDA receptor subunits GluN2A and GluN2B, along with Fyn and PSD95 proteins, were...
Semidwarfism has been used extensively in row crops and horticulture to promote yield, reduce lodging, and improve harvest index, and it might have similar benefits for trees for short-rotation forestry or energy plantations, reclamation, phytoremediation, or other applications. We studied the effects of the dominant semidwarfism transgenes GA Insensitive (GAI)...
The high accumulation rate and negligible amount of melt at Eclipse Icefield (3017 m) in the Saint Elias Range of Yukon, Canada, allows for the preservation of a high-resolution isotopic and glaciochemical records valuable for reconstruction of climatic variables. Each of the three Eclipse ice cores have a well-constrained depth–age...
Spontaneous neoplasia of the intestinal tract in sentinel and moribund zebrafish (Danio rerio) is common in some zebrafish facilities. We previously classified these tumors as adenocarcinoma, small-cell carcinoma, or carcinoma otherwise unspecified based on histomorphologic characteristics. Based on histological presentation, the primary differential diagnosis for the intestinal carcinomas was tumor...
This study represents a novel approach for intraoperative ovarian cancer treatment based on the combinatorial effect of a targeted photodynamic therapy (PDT) associated with suppression of the DJ-1 protein, one of the key players in the ROS defense of cancer cells. To assess the potential of the developed therapy, dendrimer-based...