This study represents a novel approach for intraoperative ovarian cancer treatment based on the combinatorial effect of a targeted photodynamic therapy (PDT) associated with suppression of the DJ-1 protein, one of the key players in the ROS defense of cancer cells. To assess the potential of the developed therapy, dendrimer-based...
Despite increasing consumer demand for organic food and farm products and double-digit annual sales growth, U.S. organic production is currently flat and unable to meet demand. This report presents findings from a national survey of farmers about their experiences with organic transition, exploring motivations, obstacles, and desired resources and support...
The Bering Sea and Gulf of Alaska support a number of commercially important flatfish fisheries. These high latitude ecosystems are predicted to be most immediately impacted by ongoing ocean acidification, but the range of responses by commercial fishery species has yet to be fully explored. In this study, we examined...
This study explores how a platform enables social media influencers to promulgate a consumption ideology. We show how gun influencers, or “gunfluencers,” use Instagram to link products, activities, and meanings to Second Amendment ideology—a gun-centric belief system in the United States colloquially known as “2A ideology.” Through a qualitative study...
Geographic patterns of genetic variation in wild species reflect the interplay of ecological and evolutionary processes. We assessed genetic variation in three genomes across four North American diploid strawberry taxa, with special emphasis on the gynodioecious Fragaria vesca subsp. bracteata (A.Heller) Staudt. Specifically, we sequenced one chloroplast (rpoC2) and two...
While Brettanomyces can metabolize nonesterified hydroxycinnamic acids found in grape musts/wines (caffeic, p-coumaric, and ferulic acids), it was not known whether this yeast could utilize the corresponding tartaric acid esters (caftaric, p-coutaric, and fertaric acids, respectively). Red wines from Washington and Oregon were inoculated with B. bruxellensis, while hydroxycinnamic acids...
Capturing breeding adults of colonially nesting species can entail risks of nest failure and even colony abandonment, especially in species that react strongly to human disturbance. A low-disturbance technique for capturing specific adult Double-crested Cormorants (Phalacrocorax auritus) at a ground-nesting colony was developed to reduce these risks and is described...
Polyoxoniobates are exceptional amongst polyoxometalates in that
they can potentially perform base catalysis in water, a process in
which a proton is bonded to an oxo ligand, and a hydroxyl is
released. Catalytic decomposition of chemical warfare agents such
as organofluorophosphates that were used recently in the infamous
civilian attacks...
Rates of net community production (NCP) and air-sea CO₂ flux in the Northeast Pacific subarctic, transition zone and subtropical regions (22°N–50°N, 145°W–152°W) were determined on a cruise in August–September 2008 by continuous measurement of surface values of the ratio of dissolved oxygen to argon (O₂/Ar) and the partial pressure of...
Previous game-theoretic studies of vaccination behavior typically have often assumed that populations are homogeneously mixed and that individuals are fully rational. In reality, there is heterogeneity in the number of contacts per individual, and individuals tend to imitate others who appear to have adopted successful strategies. Here, we use network-based...