The potent antitumor agent phorboxazole A was synthesized from six subunits comprising C1-C2 (115), C3-C8 (98), C9-C19 (74), C20-C32 (52), C33-C41 (84) and C42-C46 (85). Tetrahydropyrans B and C containing cis-2,6-disubstitution were fabricated via palladium(II)-mediated intramolecular alkoxycarbonylation which, in the case of tetrahydropyran C, was carried out with catalytic palladium(II)...
Drilled shaft foundation elements provide a cost-effective foundation alternative for the support of building and bridge superstructure loads. Bi-directional pile loading tests (BDPLTs) to evaluate the capacity of drilled shafts have become popular owing to their capacity to save time and effort as compared to the use of top-down loading...
Wireless LANs (WLANs) have been widely adopted and are more convenient as they are inter-connected as wireless campus networks and wireless mesh networks. However, time-sensitive multimedia applications, which
have become more popular, could suffer from long end-to-end latency in WLANs.
This is due mainly to handoff delay, which in turn...
Concrete is certainly prone to internal deteriorations or defects during the construction and operating periods. Compared with other nondestructive techniques, infrared thermography can easily detect the subsurface delamination in a very short period of time, but accurately identifying its size and depth in concrete is a very challenging task. In...
The current study investigates gender differences in behavioral regulation in four societies: the United States, Taiwan, South Korea, and China. Directly assessed individual behavioral regulation(Head–Toes–Knees–Shoulders, HTKS), teacher-rated classroom behavioral regulation (Child Behavior Rating Scale, CBRS) and a battery of school readiness assessments (mathematics, vocabulary, and early literacy) were used with...
We investigated DNA methylomes of pediatric B-cell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and high-definition microarrays, along with RNA expression profiles. Epigenetic alteration of B-ALLs occurred in two tracks: de novo methylation of small functional compartments and demethylation of large intercompartmental backbones. The deviations were exaggerated in lamina-associated...
Water quality agencies and scientists are increasingly adopting standardized sampling methodologies because of the challenges associated with interpreting data derived from dissimilar protocols. Here, we compare 13 protocols for monitoring streams from different regions and countries around the globe. Despite the spatially diverse range of countries assessed, many aspects of...
Cell death is a process of dying within biological cells that are ceasing to function. This process is essential in regulating organism development, tissue homeostasis, and to eliminate cells in the body that are irreparably damaged. In general, dysfunction in normal cellular death is tightly linked to cancer progression. Specifically,...
The coexistence problem occurs when a single wireless body area network (WBAN) is located within a multiple-WBAN
environment. This causes WBANs to suffer from severe channel interference that degrades the communication performance of each
WBAN. Since a WBAN handles vital signs that affect human life, the detection or prediction of...
In a wireless sensor network, sensor nodes are deployed in an ad hoc fashion and they deliver data packets using multihop transmission. However, transmission failures occur frequently in the multihop transmission over wireless media. Thus, a loss recovery mechanism is required to provide end-to-end reliability. In addition, because the sensor...