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Effect of Testosterone on Neuronal Morphology and Neuritic Growth of Fetal Lamb Hypothalamus-Preoptic Area and Cerebral Cortex in Primary Culture

Creator:

Reddy, Radhika C., Amodei, Rebecka, Estill, Charles T., Stormshak, Fred, Meaker, Mary, and Roselli, Charles E.

Abstract:

Testosterone plays an essential role in sexual differentiation of the male sheep brain. The ovine sexually dimorphic nucleus (oSDN), is 2 to 3 times larger in males than in females, and this sex difference is under the control of testosterone. The effect of testosterone on oSDN volume may result from...

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Article

Full Text:

Cortex in Primary Culture Reddy, R. C., Amodei, R., Estill, C. T., Stormshak, F., Meaker, M., & Roselli
Prenatal Influence of an Androgen Agonist and Antagonist on the Differentiation of the Ovine Sexually Dimorphic Nucleus in Male and Female Lamb Fetuses

Creator:

Roselli, Charles E., Reddy, Radhika C., Estill, Charles T., Scheldrup, Melissa, Meaker, Mary, Stormshak, Fred, and Montilla, Hernán J.

Abstract:

The ovine sexually dimorphic nucleus (oSDN) is 2 times larger in rams than in ewes. Sexual differentiation of the oSDN is produced by testosterone exposure during the critical period occurring between gestational day (GD)60 and GD90 (term, 147 d). We tested the hypothesis that testosterone acts through the androgen receptor...

Resource Type:

Article