Index Catalog // ScholarsArchive@OSU

Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function

Creator:: He, Yue, Yam, Candice, Pomraning, Kyle, Chin, Jacqueline S. R., Yew, Joanne Y., Freitag, Michael, and Oliferenko, Snezhana
Abstract:: Excess fatty acids and sterols are stored as triacylglycerols and sterol esters in specialized cellular organelles, called lipid droplets. Understanding what determines the cellular amount of neutral lipids and their packaging into lipid droplets is of fundamental and applied interest. Using two species of fission yeast, we show that cycling...
Resource Type:: Article
Full Text:: function. Molecular Biology of the Cell, 25(25), 4083-4095. doi:10.1091/mbc.E14-03-0832 10.1091/mbc.E14

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop

Creator:: Adams, Paul D., Aertgeerts, Kathleen, Bauer, Cary, Bell, Jeffrey A., Berman, Helen M., Bhat, Talapady N., Blaney, Jeff M., Bolton, Evan, Bricogne, Gerard, Brown, David, Burley, Stephen K., Case, David A., Clark, Kirk L., Darden, Tom, Emsley, Paul, Feher, Victoria A., Feng, Zukang, Groom, Colin R., Harris, Seth F., Hendle, Jorg, Holder, Thomas, Joachimiak, Andrzej, Kleywegt, Gerard J., Krojer, Tobias, Marcotrigiano, Joseph, Mark, Alan E., Markley, John L., Miller, Matthew, Minor, Wladek, Montelione, Gaetano T., Murshudov, Garib, Nakagawa, Atsushi, Nakamura, Haruki, Nicholls, Anthony, Nicklaus, Marc, Nolte, Robert T., Padyana, Anil K., Peishoff, Catherine E., Pieniazek, Susan, Read, Randy J., Shao, Chenghua, Sheriff, Steven, Smart, Oliver, Soisson, Stephen, Spurlino, John, Stouch, Terry, Svobodova, Radka, Tempel, Wolfram, Terwilliger, Thomas C., Tronrud, Dale, Velankar, Sameer, Ward, Suzanna C., Warren, Gregory L., Westbrook, John D., Williams, Pamela, Yang, Huanwang, and Young, Jasmine
Abstract:: Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
Resource Type:: Article

Expression, Splicing, and Evolution of the Myosin Gene Family in Plants

Creator:: Peremyslov, Valera V., Mockler, Todd C., Filichkin, Sergei A., Fox, Samuel E., Jaiswal, Pankaj, Makarova, Kira S., Koonin, Eugene V., and Dolja, Valerian V.
Abstract:: Plants possess two myosin classes, VIII and XI. The myosins XI are implicated in organelle transport, filamentous actin organization, and cell and plant growth. Due to the large size of myosin gene families, knowledge of these molecular motors remains patchy. Using deep transcriptome sequencing and bioinformatics, we systematically investigated myosin...
Resource Type:: Article

Evidence for geomagnetic imprinting as a homing mechanism in Pacific salmon

Creator:: Putnam, Nathan F., Lohmann, Kenneth J., Putnam, Emily M., Quinn, Thomas P., Klimley, A. Peter, and Noakes, David L. G.
Abstract:: In the final phase of their spawning migration, Pacific salmon use chemical cues to identify their home river, but how they navigate from the open ocean to the correct coastal area has remained enigmatic [1]. To test the hypothesis that salmon imprint on the magnetic field that exists where they...
Resource Type:: Article
Full Text:: Highlights: • Sockeye salmon use geomagnetic imprinting as a homing mechanism. • The homing route of

Menage a trois : an evolutionary interplay between human papilloma virus, a tumor and a woman

Creator:: Shulzhenko, Natalia, Lyng, Heidi, Sanson, Gerdine F., and Morgun, Andrey
Abstract:: Cervical cancer is the third most common cancer in women with Human papillomavirus (HPV) being a key etiologic factor of this devastating disease. In this article, we describe modern advances in the genomics and transcriptomics of cervical cancer that led to uncovering the key gene drivers. We also introduce, herein,...
Resource Type:: Article
Full Text:: drive cell cycle, antiviral response, and inhibit cell differentiation. The new model may help

Zebrafish models for translational neuroscience research: from tank to bedside

Creator:: Stewart, Adam Michael, Braubach, Oliver, Spitsbergen, Jan, Gerlai, Robert, and Kalueffl, Allan V.
Abstract:: The zebrafish (Danio rerio) is emerging as a new important species for studying brain mechanisms and its deficits. Focusing on selected CNS disorders (brain cancer, epilepsy and anxiety) and using them as examples, we discuss the value of zebrafish models in translational neuroscience, and their contribution to neuroimaging, circuit-level and...
Resource Type:: Article
Full Text:: ), 264-278. doi:10.1016/j.tins.2014.02.011 10.1016/j.tins.2014.02.011 Elsevier/Cell Press Accepted

Taking the Next Step: Building an Arabidopsis Information Portal

Creator:: International Arabidopsis Informatics Consortium, Bastow, Ruth, Beynon, Jim, Brendel, Volker, Dooley, Rion, Friesner, Joanna, Grotewold, Erich, Huala, Eva, Loraine, Ann, Meyers, Blake, Pires, J. Chris, Provart, Nicholas, Stanzione, Dan, Town, Chris, and Ware, Doreen
Abstract:: The Arabidopsis Information Portal (AIP), a resource expected to provide access to all community data and combine outputs into a single user-friendly interface, has emerged from community discussions over the last 23 months. These discussions began during two closely linked workshops in early 2010 that established the International Arabidopsis Informatics...
Resource Type:: Article
Full Text:: Informatics Consortium. (2012). Taking the next step: building an Arabidopsis information portal. Plant Cell

Data for Investigating Protein-lipid-membrane Interactions in Plant Cells using Bimolecular Fluorescence Complementation

Creator:: Tao, Kai
Abstract:: The dataset here is used as a document file for presenting supplementary videos in the dissertation Tao, K. (2018). Investigating protein-lipid-membrane interactions in Plant Cells using Bimolecular Fluorescence Complementation (Doctoral dissertation). Keywords: Protein, Lipid, Membrane, Plant Cells, Fluorescent Imaging
Resource Type:: Dataset

Identification of Myosin XI Receptors in Arabidopsis Defines a Distinct Class of Transport Vesicles

Creator:: Peremyslov, Valera V., Morgun, Eva A., Kurth, Elizabeth G., Makarova, Kira S., Koonin, Eugene V., and Dolja, Valerian V.
Abstract:: To characterize the mechanism through which myosin XI-K attaches to its principal endomembrane cargo, a yeast two-hybrid library of Arabidopsis thaliana cDNAs was screened using the myosin cargo binding domain as bait. This screen identified two previously uncharacterized transmembrane proteins (hereinafter myosin binding proteins or MyoB1/2) that share a myosin...
Resource Type:: Article
Full Text:: and Wasteneys, 2013). The extensive dynamics of the plant cell interior are powered by the myosins XI

A Phytophthora sojae Glycoside Hydrolase 12 Protein Is a Major Virulence Factor during Soybean Infection and Is Recognized as a PAMP

Creator:: Ma, Zhenchuan, Song, Tianqiao, Zhu, Lin, Ye, Wenwu, Wang, Yang, Shao, Yuanyuan, Dong, Suomeng, Zhang, Zhengguang, Dou, Daolong, Zheng, Xiaobo, Tyler, Brett M., and Wang, Yuanchao
Abstract:: We identified a glycoside hydrolase family 12 (GH12) protein, XEG1, produced by the soybean pathogen Phytophthora sojae that exhibits xyloglucanase and β-glucanase activity. It acts as an important virulence factor during P. sojae infection but also acts as a pathogen-associated molecular pattern (PAMP) in soybean (Glycine max) and solanaceous species,...
Resource Type:: Article

ScholarsArchive@OSU

Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop

Expression, Splicing, and Evolution of the Myosin Gene Family in Plants

Evidence for geomagnetic imprinting as a homing mechanism in Pacific salmon

Menage a trois : an evolutionary interplay between human papilloma virus, a tumor and a woman

Zebrafish models for translational neuroscience research: from tank to bedside

Taking the Next Step: Building an Arabidopsis Information Portal

Data for Investigating Protein-lipid-membrane Interactions in Plant Cells using Bimolecular Fluorescence Complementation

Identification of Myosin XI Receptors in Arabidopsis Defines a Distinct Class of Transport Vesicles

A Phytophthora sojae Glycoside Hydrolase 12 Protein Is a Major Virulence Factor during Soybean Infection and Is Recognized as a PAMP

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