The present studies investigated the cellular mechanisms for the detrimental effects of high dose whole body γ-irradiation on bone. In addition, radioadaptation and bone marrow transplantation were assessed as interventions to mitigate the skeletal complications of irradiation. Increased trabecular thickness and separation and reduced cancellous bone volume fraction, connectivity density,...
Endoxifen has recently been identified as the predominant active metabolite of tamoxifen and is currently being developed as a novel hormonal therapy for the treatment of endocrine sensitive breast cancer. Based on past studies in breast cancer cells and model systems, endoxifen classically functions as an anti-estrogenic compound. Since estrogen...
This special issue presents short-term ecological effects of restoration treatments imposed as part of the Sagebrush Steppe Treatment Evaluation Project (SageSTEP), and summarizes
public attitude survey results related to restoration efforts.
Funded by the US Joint Fire Science Program (JFSP; 2005-2011), the Bureau of Land Management (BLM; 2011 to present),...
As part of the Sagebrush Steppe Treatment Evaluation Project (SageSTEP), butterflies were surveyed pre-treatment and up to four years post-treatment at 16 widely distributed sagebrush steppe sites in the interior West. Butterfly populations and communities were analyzed in response to treatments (prescribed fire, mechanical, herbicide) designed to restore sagebrush steppe...
Mutations in the metallo-protein Cu/Zn-superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS) in humans and an
expression level-dependent phenotype in transgenic rodents. We show that oral treatment with the therapeutic agent diacetyl-bis(4-methylthiosemicarbazonato)copper[superscript II] [Cu[superscript II](atsm)] increased the concentration of mutant SOD1 (SOD1G37R) in ALS model mice, but paradoxically improved locomotor...
Direct determination of the irreversible turbulent flux of salinity in the ocean has not been possible because of the complexity of measuring salinity on the smallest scales over which it mixes. Presented is an analysis of turbulent salinity microstructure from measurements using a combined fast-conductivity/temperature probe on a slowly falling...
The RNA genome of tobacco etch virus (TEV), a plant potyvirus, functions as an mRNA for synthesis of a
346-kilodalton polyprotein that undergoes extensive proteolytic processing. The RNA lacks a normal 5' cap
structure at its terminus, which suggests that the mechanism of translational initiation differs from that of a...
Published July 1993. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
African Americans in predominantly White institutions often carry a greater load than their positions describe. While researchers have explored the unique role of African Americans in higher education (Cook, 1996; Diller & Moule, 2005; Jones, 2001; King & Castenell, 2001; Ladson-Billings, 1997; Maboleka & Green, 2001; Moule, 2004; Powell, 1999;...