The improvement of the agricultural and wine-making qualities of the grapevine (Vitis vinifera) is hampered by adherence to traditional varieties, the recalcitrance of this plant to genetic modifications, and public resistance to genetically modified organism (GMO) technologies. To address these challenges, we developed an RNA virus-based vector for the introduction...
A retrovirus homologue gene of cellular cyclin D₁, walleye dermal sarcoma virus rv-cyclin
gene (orf A or rv-cyclin), was expressed in the livers of zebrafish under the control
of liver fatty-acid binding protein (lfabp) promoter. To prevent possible fatality caused
by over-expression of the oncogene, the GAL4/UAS system was used...
Grapevine leafroll disease (GLD) is one of the most important grapevine viral diseases affecting grapevines worldwide. The impact on vine health, crop yield, and quality is difficult to assess due to a high number of variables, but significant economic losses are consistently reported over the lifespan of a vineyard if...
Important progress in understanding replication, interactions with host plants, and evolution of closteroviruses enabled engineering of several vectors for gene expression and virus-induced gene silencing. Due to the broad host range of closteroviruses, these vectors expanded vector applicability to include important woody plants such as citrus and grapevine. Furthermore, large...
Herbicide resistance is an exceptional marker to quantify gene flow. Quantification of pollen-, seed-, and vegetative propagule-mediated gene flow provides key weed biology information. Pollen-mediated gene flow influences the genetic variance within a population, the frequency of multiple or polygenic herbicide resistance, and the evolutionary dynamics of a species. Seed-mediated...
Groundnut ringspot virus (GRSV) and Tomato chlorotic spot virus
(TCSV) are two emerging tospoviruses in Florida. In a survey of the
southeastern United States, GRSV and TCSV were frequently detected in
solanaceous crops and weeds with tospovirus-like symptoms in south
Florida, and occurred sympatrically with Tomato spotted wilt virus (TSWV)...
Cervical cancer is the third most common cancer in women with Human papillomavirus (HPV) being a key etiologic factor of this devastating disease. In this article, we describe modern advances in the genomics and transcriptomics of cervical cancer that led to uncovering the key gene drivers. We also introduce, herein,...
Viruses were defined as one of the two principal types of organisms
in the biosphere, namely, as capsid-encoding organisms in
contrast to ribosome-encoding organisms, i.e., all cellular life
forms. Structurally similar, apparently homologous capsids are
present in a huge variety of icosahedral viruses that infect bacteria,
archaea, and eukaryotes. These...
In eukaryotes, ARGONAUTE proteins (AGOs) associate with microRNAs (miRNAs), short interfering RNAs (siRNAs), and other classes of small RNAs to regulate target RNA or target loci. Viral infection in plants induces a potent and highly specific antiviral RNA silencing response characterized by the formation of virus-derived siRNAs. Arabidopsis thaliana has...
Background: Potato virus Y (PVY) is one of the most important plant viruses affecting potato production. The
interactions between potato and PVY are complex and the outcome of the interactions depends on the potato
genotype, the PVY strain, and the environmental conditions. A potato cultivar can induce resistance to a...