The promise of epigenome-wide association studies (EWAS) and cancer specific somatic changes in improving our understanding of cancer coupled with the decreasing cost and increasing coverage of DNA methylation microarrays, has brought about a surge in the use of these technologies. Here, we aim to provide both a review of...
Historians and sociologists of science often identify the efflorescence of social stud ies of science with the work of postwar American intellectuals such as Robert K. Merton and Thomas S. Kuhn. They often also refer to the views of Michael Polanyi (1891-1976) on the roles of tacit knowledge, apprenticeship, social...
In early August 2014, the municipality of Toledo, OH (USA) issued a ‘do not drink’ advisory on their water supply directly affecting over 400,000 residential customers and hundreds of businesses (Wilson, 2014). This order was attributable to levels of microcystin, a potent liver toxin, which rose to 2.5 μg L⁻¹...
Knowledge of the shear stress on a fault during slip is necessary
for a physically-based understanding of earthquakes. Borehole
temperature measurements inside the fault zone immediately after
an earthquake can record the energy dissipated by this stress. In the
first Wenchuan Earthquake Fault Zone Scientific Drilling Project
hole (Sichuan province,...
Changes in the spatial distribution of U.S. west coast bottom-trawl effort in relation
to areas of prime habitat for rockfish Sebastes spp. were evaluated between 1992 and 2001. Prime trawlable rockfish habitat (PTRH) was defined based on the spatial distribution of high rockfish catches from logbook data for 1992–1995. Bottom-trawl...
Pyrenophora tritici-repentis (Ptr), a necrotrophic fungus and the causal agent of tan spot of wheat, produces one or a combination of host-selective toxins (HSTs) necessary for disease development. The two most studied toxins produced by Ptr, Ptr ToxA (ToxA) and Ptr ToxB (ToxB), are proteins that cause necrotic or chlorotic...
Pyrenophora tritici-repentis (Ptr), a necrotrophic fungus and the causal agent of tan spot of wheat, produces one or a combination of host-selective toxins (HSTs) necessary for disease development. The two most studied toxins produced by Ptr, Ptr ToxA (ToxA) and Ptr ToxB (ToxB), are proteins that cause necrotic or chlorotic...