BACKGROUND: Little is known about α-tocopherol’s bioavailability
as a constituent of food or its dependence on a subject’s age.
OBJECTIVE: To evaluate the α-tocopherol bioavailability from food,
we used collard greens grown in deuterated water (²H collard
greens) as a source of deuterium-labeled (²H) α-tocopherol consumed
by younger and older...
The zebrafish (Danio rerio) is emerging as a new important species for studying brain mechanisms and its deficits. Focusing on selected CNS disorders (brain cancer, epilepsy and anxiety) and using them as examples, we discuss the value of zebrafish models in translational neuroscience, and their contribution to neuroimaging, circuit-level and...
How do you test a program when only a single user, with no expertise in software testing, is able to determine if the
program is performing correctly? Such programs are common today in the form of machine-learned classifiers. We consider the
problem of testing this common kind of machine-generated program...
The protein palmitoylation cycle has been shown to be important for protein signaling and synaptic plasticity. Data from our lab showed a change in the palmitoylation status of certain proteins with age. A greater percentage of the NMDA receptor subunits GluN2A and GluN2B, along with Fyn and PSD95 proteins, were...
We investigated how large carnivores, herbivores, and plants may be linked to the maintenance of native species biodiversity through trophic
cascades. The extirpation of wolves (Canis lupus) from Yellowstone National Park in the mid-1920s and their reintroduction in 1995 provided the
opportunity to examine the cascading effects of carnivore–herbivore interactions...
Like most ecological communities, aspen (Populus tremuloides) forests are influenced by a synergy of bottom-up (resources-driven) and top-down (predator-driven) processes. Since the 1920s, ecologists have observed the decline of many aspen communities throughout the Intermountain West. The extent and possible drivers of this decline are topics of much recent scientific...
Body size is known to correlate with many aspects of life history in birds, and this knowledge can be used to manage and conserve bird species. However, few studies have compared the wintering ecology of sympatric subspecies that vary significantly in body size. We used radiotelemetry to examine the relationship...
Diets of juvenile coho Oncorhynchus kisutch and Chinook O. tshawytscha salmon
are made up primarily of winter-spawning fish taxa in the late-larval and early juvenile stages that
are undersampled in plankton and larger trawl nets. Although we have no direct measure of the
availability of fish prey important to juvenile...
As colony-specific wintering ecology of small and medium-sized seabirds is poorly understood, it has been generally assumed that winter conditions have the same effect on all individuals from any given colony. However, advances in global positioning technology now allow researchers to investigate movements of smaller seabirds. We tracked black-legged kittiwakes...
The Lewis and Clark journals contain some of the earliest and most detailed written descriptions of a large part of the United States before
Euro-American settlement.We used the journal entries to assess the influence of humans on wildlife distribution and abundance. Areas with
denser human population, such as the Columbia...