Saccharomyces cerevisiae contains three NAD⁺/NADH kinases, one of which is localized in
mitochondria and phosphorylates NADH in preference to NAD⁺. Strand et al (Euk. Cell
2:809 (2003)) reported that a yeast mutation in POS5, which encodes the mitochondrial
NADH kinase, is a mutator, specific for mitochondrial genes. Because of the...
Obesity contributes to increased risk for several chronic diseases including cardiovascular disease and type 2 diabetes. Xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), was tested for efficacy on biomarkers of metabolic syndrome in 4 week old Zucker fa/fa rats, a rodent model of obesity. Rats received daily oral doses...
The protein palmitoylation cycle has been shown to be important for protein signaling and synaptic plasticity. Data from our lab showed a change in the palmitoylation status of certain proteins with age. A greater percentage of the NMDA receptor subunits GluN2A and GluN2B, along with Fyn and PSD95 proteins, were...
1. Ecologists, outdoor professionals and the public work and play in lands with complex histories. Part of decolonizing our professional and recreational practices is to expose settler colonial biases and recognize the histories of colonized lands and the peoples who have stewarded these lands for millennia prior to colonization.
2....
Like most ecological communities, aspen (Populus tremuloides) forests are influenced by a synergy of bottom-up (resources-driven) and top-down (predator-driven) processes. Since the 1920s, ecologists have observed the decline of many aspen communities throughout the Intermountain West. The extent and possible drivers of this decline are topics of much recent scientific...
Wildfire risk in temperate forests has become a nearly intractable problem that can be characterized as a socioecological “pathology”: that is, a set of complex and problematic interactions among social and ecological systems across multiple spatial and temporal scales. Assessments of wildfire risk could benefit from recognizing and accounting for...
Purpose/Objective: According to Social Identity Theory, minority group members, like people with disabilities, manage stigma by either “passing” as majority group members or identifying with their minority group. Approximately 15% of the world’s population has a disability, but only a fraction of those individuals identify themselves as people with disabilities....
As the elderly population increases, more family, friends, and paid service providers assist them with consumption activities in a group that the authors conceptualize as the elderly consumption ensemble (ECE). Interviews with members of eight ECEs demonstrate consumption in advanced age as a group phenomenon rather than an individual one,...
In organizational management, researchers and managers study separations or faultlines that occur in diverse teams when members
form subgroups based on the alignment of multiple demographic characteristics. The team faultline concept is operationalized
using multivariate cluster analysis—analysts use faultline measures to identify subgroups/clusters in a team and to quantify how...
Pollen analyses of sediments from Holes 1019C, 1019E, 1020C, and 1020D as well as piston Core EW9504-17 provide
continuous, chronostratigraphically controlled proxy vegetation and climate data for coastal northwest North America for the
last ~500 k.y. Systematic changes in the representation of the diagnostic components of northern California plant assemblages...