Excess fat intake can increase lipid oxidation and expression of mitochondrial proteins, indicating remodeling of the mitochondrial proteome. Yet intermediates of lipid oxidation also accumulate, indicating a relative insufficiency to completely oxidize lipids. We investigated remodeling of the mitochondrial proteome to determine mechanisms of changes in lipid oxidation following high-fat...
Because of the intangible nature of online shopping, consumers perceive online shopping as being risky. This study examined how this risk can be reduced specifically by using a more effective online product presentation method. A combination of the number of product views (one and four) and size (small and large)...
Background: Relative to heterosexual youth, sexual minority youth exhibit increased substance use. Risk for polysubstance use, which magnifies drug-related harms, remains largely unexamined for sexual minority youth. This investigation used a nationally-representative dataset to compare polysubstance use patterns between sexual minority and heterosexual youth.
Methods: The cross-sectional 2015 CDC's Youth...
Vibrio cholerae, an etiological agent of cholera, circulates between aquatic reservoirs and the human gastrointestinal tract. The
type II secretion (T2S) system plays a pivotal role in both stages of the lifestyle by exporting multiple proteins, including cholera
toxin. Here, we studied the kinetics of expression of genes encoding the...
We propose a mathematical formulation for strategic relay network design and dispatching method selection for full truckload transportation. The proposed model minimizes total transportation and installation costs of a mixed fleet dispatching system combining relay network and point-to-point dispatching. Operational constraints such as maximum driver tour length and load circuity...
We investigated habitat attributes related to the occupancy of the globally rare and endangered
epiphytic lichen, Erioderma pedicellatum, in a newly discovered (2009) population center in Denali National
Park and Preserve (DNPP), Alaska. We measured forest, tree and epiphytic lichen community
characteristics on eighty-five systematically selected plots in four study...
Bathymetry and gravity data collected during Legs 5, 6, and 7 of the 1993 GLORIA Expedition and the recently released 2-min altimetry-derived global gravity grid are used to determine the effective elastic thickness of the lithosphere along the Easter Seamount Chain (ESC). Forward modeling, admittance, and coherence methods yield consistent...
Background Maternal blood total mercury (THg) is a biomarker for prenatal methylmercury (MeHg) exposure. Few studies have quantified both blood THg and MeHg during pregnancy, and few studies have reported longitudinal trends.
Objectives We analyzed blood THg and MeHg in a cohort of pregnant mothers in Charleston, South Carolina (n...
A key challenge for resource and land managers is predicting the consequences of climate warming on streamflow and water
resources. During the last century in the western United States, significant reductions in snowpack and earlier snowmelt have led
to an increase in the fraction of annual streamflow during winter and...
Floods are the most frequent natural disaster, causing more loss of life and property than any other in the USA. Floods also strongly influence the structure and function of watersheds, stream channels, and aquatic ecosystems. The Pacific Northwest is particularly vulnerable to climatically driven changes in flood frequency and magnitude,...