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Mycobacterium avium Biofilm Attenuates Mononuclear Phagocyte Function by Triggering Hyperstimulation and Apoptosis during Early Infection

Creator:: Rose, Sasha J. and Bermudez, Luiz E.
Abstract:: Mycobacterium avium subsp. hominissuis is an opportunistic human pathogen that has been shown to form biofilm in vitro and in vivo. Biofilm formation in vivo appears to be associated with infections in the respiratory tract of the host. The reasoning behind how M. avium subsp. hominissuis biofilm is allowed to...
Resource Type:: Article
Full Text:: Early Infection Rose, S. J., & Bermudez, L. E. (2014). Mycobacterium avium Biofilm Attenuates

Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics

Creator:: Rose, Sasha J., Babrak, Lmar M., and Bermudez, Luiz E.
Abstract:: Mycobacterium avium subsp. hominissuis is an opportunistic pathogen that is associated with biofilm-related infections of the respiratory tract and is difficult to treat. In recent years, extracellular DNA (eDNA) has been found to be a major component of bacterial biofilms, including many pathogens involved in biofilm-associated infections. To date, eDNA...
Resource Type:: Article
Full Text:: , and Tolerance to Antibiotics Rose, S. J., Babrak, L. M., & Bermudez, L. E. (2015). Mycobacterium

Aircraft measurements of high average charges on cloud drops in layer clouds

Creator:: Beard, Kenneth V., Ochs, Harry T., III, and Twohy, Cynthia
Abstract:: The first reliable aircraft measurements of characteristic cloud drop charges were obtained by utilizing a counterflow virtual impactor to substantially increase charge sensitivity and eliminate spurious contact charging that contaminated previous aircraft measurements. We find average drop charges more than an order of magnitude larger than expected from mountain surface...
Resource Type:: Article
Full Text:: cloud drops in layer clouds Kenneth V. Beard,1,2 Harry T. Ochs III,1,2 and Cynthia H. Twohy3 Received

Nitrogenated organic aerosols as cloud condensation nuclei

Creator:: Twohy, Cynthia, Anderson, J. R., and Crozier, P. A.
Abstract:: One important role of anthropogenic aerosol particles is their influence on climate by acting as cloud condensation nuclei. However, these particles are diverse in composition and mixing state, and our knowledge of which particle types act as cloud condensation nuclei is incomplete. Here we present direct measurements of individual organic...
Resource Type:: Article
Full Text:: detectable with EELS). Figure 2c shows the derived elemental profiles. Relative atomic concentration ratios

Mycobacterium tuberculosis Alters the Metalloprotease Activity of the COP9 Signalosome

Creator:: Danelishvili, Lia, Babrak, Lmar, Rose, Sasha J., Everman, Jamie, and Bermudez, Luiz E.
Abstract:: Inhibition of apoptotic death of macrophages by Mycobacterium tuberculosis represents an important mechanism of virulence that results in pathogen survival both in vitro and in vivo. To identify M. tuberculosis virulence determinants involved in the modulation of apoptosis, we previously screened a transposon bank of mutants in human macrophages, and...
Resource Type:: Article
Full Text:: of the COP9 Signalosome Danelishvili, L., Babrak, L., Rose, S. J., Everman, J., & Bermudez, L. E

Effective Radius of Ice Cloud Particle Populations Derived from Aircraft Probes

Creator:: Heymsfield, Andrew J., Schmitt, Carl, Bansemer, Aaron, van Zadelhoff, Gerd-Jan, McGill, Matthew J., Twohy, Cynthia, and Baumgardner, Darrel
Abstract:: The effective radius (r[subscript]e) is a crucial variable in representing the radiative properties of cloud layers in general circulation models. This parameter is proportional to the condensed water content (CWC) divided by the extinction (σ). For ice cloud layers, parameterizations for r[subscript]e have been developed from aircraft in situ measurements...
Resource Type:: Article
Full Text:: Bilt, Netherlands MATTHEW J. MCGILL NASA Goddard Space Flight Center, Greenbelt, Maryland CYNTHIA

Improvements to an Empirical Parameterization of Heterogeneous Ice Nucleation and Its Comparison with Observations

Creator:: Phillips, Vaughan T. J., Demott, Paul J., Andronache, Constantin, Pratt, Kerri A., Prather, Kimberly A., Subramanian, R., and Twohy, Cynthia
Abstract:: A framework for an empirical parameterization (EP) of heterogeneous nucleation of ice crystals by multiple species of aerosol material in clouds was proposed in a 2008 paper by the authors. The present paper reports improvements to specification of a few of its empirical parameters. These include temperatures for onset of...
Resource Type:: Article
Full Text:: . DEMOTT,1 CONSTANTIN ANDRONACHE,# KERRI A. PRATT,@,11 KIMBERLY A. PRATHER,@ R. SUBRAMANIAN,& AND CYNTHIA

Evidence of nitric acid uptake in warm cirrus anvil clouds during the NASA TC4 campaign

Creator:: Scheuer, Eric, Dibb, Jack E., Twohy, Cynthia, Rogers, David C., Heymsfield, Andrew J., and Bansemer, Aaron
Abstract:: Uptake ofHNO₃ onto cirrus ice may play an important role in tropospheric NOx cycling. Discrepancies between modeled and in situ measurements of gas‐phase HNO₃ in the troposphere suggest that redistribution and removal mechanisms by cirrus ice have been poorly constrained. Limited in situ measurements have provided somewhat differing results and...
Resource Type:: Article
Full Text:: Cynthia Twohy,2 David C. Rogers,3 Andrew J. Heymsfield,4 and Aaron Bansemer4 Received 24 June 2009

Ice in Clouds Experiment—Layer Clouds. Part I: Ice Growth Rates Derived from Lenticular Wave Cloud Penetrations

Creator:: Heymsfield, Andrew J., Field, Paul R., Bailey, Matt, Rogers, Dave, Stith, Jeffrey, Twohy, Cynthia, Wang, Zhien, and Haimov, Samuel
Abstract:: Lenticular wave clouds are used as a natural laboratory to estimate the linear and mass growth rates of ice particles at temperatures from -20° to -32°C and to characterize the apparent rate of ice nucleation at water saturation at a nearly constant temperature. Data are acquired from 139 liquid cloud...
Resource Type:: Article
Full Text:: . FIELD,1 MATT BAILEY,# DAVE ROGERS,* JEFFREY STITH,* CYNTHIA TWOHY,@ ZHIEN WANG,& AND SAMUEL HAIMOV

Anomalous porosity preservation and preferential accumulation of gas hydrate in the Andaman accretionary wedge, NGHP-01 site 17A

Creator:: Rose, Kelly K., Johnson, Joel E., Torres, Marta E., Hong, Wei-Li, Giosan, Liviu, Solomon, Evan A., Kastner, Miriam, Cawthern, Thomas, Long, Philip E., and Schaef, H. Todd
Abstract:: In addition to well established properties that control the presence or absence of the hydrate stability zone, such as pressure, temperature, and salinity, additional parameters appear to influence the concentration of gas hydrate in host sediments. The stratigraphic record at Site 17A in the Andaman Sea, eastern Indian Ocean, illustrates...
Resource Type:: Article
Full Text:: -01 site 17A Rose, K. K., Johnson, J. E., Torres, M. E., Hong, W. L., Giosan, L., Solomon, E. A

ScholarsArchive@OSU

Mycobacterium avium Biofilm Attenuates Mononuclear Phagocyte Function by Triggering Hyperstimulation and Apoptosis during Early Infection

Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics

Aircraft measurements of high average charges on cloud drops in layer clouds

Nitrogenated organic aerosols as cloud condensation nuclei

Mycobacterium tuberculosis Alters the Metalloprotease Activity of the COP9 Signalosome

Effective Radius of Ice Cloud Particle Populations Derived from Aircraft Probes

Improvements to an Empirical Parameterization of Heterogeneous Ice Nucleation and Its Comparison with Observations

Evidence of nitric acid uptake in warm cirrus anvil clouds during the NASA TC4 campaign

Ice in Clouds Experiment—Layer Clouds. Part I: Ice Growth Rates Derived from Lenticular Wave Cloud Penetrations

Anomalous porosity preservation and preferential accumulation of gas hydrate in the Andaman accretionary wedge, NGHP-01 site 17A

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