The CCAAT/enhancer binding proteins (C/EBPs) are transcription factors involved in hematopoietic cell development and
induction of several inflammatory mediators. C/EBPε is expressed only in myeloid cells including monocytes/macrophages.
Atherosclerosis is an inflammatory disorder of the vascular wall and circulating immune cells such as monocytes/macrophages. Mice deficient in the low density...
A global-scale three dimensional atmospheric transport and chemistry model was applied to simulate transpacific transport of Benzo[a]pyrene (BaP) emitted from Asia. The model results were compared with observations at six monitoring sites. The annual mean and seasonal variation of transport patterns and the contributions of different Asian source regions to...
Using microRNA array analyses of in vitro HIV-1-infected CD4(+) cells, we find that several host microRNAs are significantly up- or downregulated around the time HIV-1 infection peaks in vitro. While microRNA-223 levels were significantly enriched in HIV-1-infected CD4(superscript+)CD8(superscript-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the...