BackgroundEpidemiological evidence suggests that arsenic (As) exposure during pregnancy may reduce infant birth weight. One significant source of As exposure is diet; thus, As may indirectly affect infant growth by mediating the effect of maternal diet on birth weight (BW). This study evaluated the potential mediating effect of As in...
Antisense oligonucleotide (AO)-mediated exon-skipping therapeutics shows great promise in correcting frame-disrupting mutations in the DMD gene for Duchenne muscular dystrophy. However, insufficient systemic delivery limits clinical adoption. Previously, we showed that a glucose/fructose mixture augmented AO delivery to muscle in mdx mice. Here, we evaluated if fructose alone could enhance...
The results of a new multispectral infrared retrieval scheme for obtaining fractional cloud cover and 11-μm emissivity are compared with those of the spatial coherence method which obtains fractional cloud cover assuming that the clouds are opaque at infrared wavelengths. Both methods are applied to 4-km NOAA advanced very high...
Hot spot–mid-ocean ridge interactions cause many of the largest structural and chemical anomalies in Earth’s ocean basins. Correlated geophysical and geochemical anomalies are widely explained by mantle plumes that deliver hot and compositionally distinct material toward and along mid-ocean ridges. Compositional anomalies are seen in trace element and isotope ratios,...
We present a generalized estimating equations approach for estimating the concordance correlation coefficient and the
kappa coefficient from sample survey data. The estimates and their accompanying standard error need to correctly account
for the sampling design. Weighted measures of the concordance correlation coefficient and the kappa coefficient, along with
the...
Compared to conventional amorphous silicon (a-Si) TFTs, amorphous metal oxide TFTs have superior device performance such as
higher mobility, better sub-threshold swing, and lower off-state current. Amorphous metal oxide TFTs have an additional advantage
on the device uniformity due to the lack of grain boundary issues in the poly-Si TFTs....
Expectations for technology proficiency in counseling and counselor education have increased; nevertheless, very little information is available in the counseling literature which describes how to effectively evaluate online resources from a design and utility standpoint. This study provides a model for such assessments, employing an affordable small scale usability study...
Growth increment widths from hard structures of marine and freshwater fish and bivalve species are increasingly used to model growth and elucidate relationships with environmental variability. Fully characterizing the intrinsic age-related growth variation among individuals within and between populations, while estimating the extrinsic environmental effects simultaneously, can be challenging. Using...
In 1989, we conducted an onshore/offshore seismic experiment to image the crustal structure of the Cascadia forearc. In this paper, we discuss the processing and interpretation of a multichannel seismic reflection profile across the continental margin that was collected as part of this effort. This profile reveals several features of...
The effect of non-zero, but small, viscosity and diffusivity on the marginal stability
of a stably stratified shear flow is examined by making perturbations around the
neutral solution for an inviscid and non-diffusive flow. The results apply to turbulent
flows in which horizontal and vertical turbulent transports of momentum and...