Index Catalog // ScholarsArchive@OSU

Label-Free Proteomics Assisted by Affinity Enrichment for Elucidating the Chemical Reactivity of the Liver Mitochondrial Proteome toward Adduction by the Lipid Electrophile 4-hydroxy-2-nonenal (HNE)

Creator:: Tzeng, Shin-Cheng and Maier, Claudia S.
Abstract:: The analysis of oxidative stress-induced post-translational modifications remains challenging due to the chemical diversity of these modifications, the possibility of the presence of positional isomers and the low stoichiometry of the modified proteins present in a cell or tissue proteome. Alcoholic liver disease (ALD) is a multifactorial disease in which...
Resource Type:: Article
Full Text:: , USA *Correspondence: Claudia S. Maier claudia.maier@oregonstate.edu † Present Address: Shin-Cheng

Protein modifications by electrophilic lipoxidation products: Adduct formation, chemical strategies and tandem mass spectrometry for their detection and identification

Creator:: Vasil'ev, Yury V., Tzeng, Shin-Chen, Huang, Lin, and Maier, Claudia S.
Abstract:: The post-translational modification of proteins by electrophilic oxylipids is emerging as an important mechanism that contributes to the complexity of proteomes. Enzymatic and non-enzymatic oxidation of biological lipids results in the formation of chemically diverse electrophilic carbonyl compounds, such as 2-alkenals and 4-hydroxy alkenals, epoxides and eicosanoids with reactive cyclopentenone...
Resource Type:: Article

¹⁸O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes

Creator:: Kirkwood, Jay S., Miranda, Cristobal L., Bobe, Gerd, Maier, Claudia S., and Stevens, Jan F.
Abstract:: The differentiation of precursor cells into mature adipocytes (adipogenesis) has been an area of increased focus, spurred by a rise in obesity rates. Though our understanding of adipogenesis and its regulation at the cellular level is growing, many questions remain, especially regarding the regulation of the metabolome. The 3T3-L1 cell...
Resource Type:: Article

Surface-exposed proteins of pathogenic mycobacteria and the role of cu-zn superoxide dismutase in macrophages and neutrophil survival

Creator:: McNamara, Michael, Tzeng, Shin-Cheng, Maier, Claudia, Wu, Martin, and Bermudez, Luiz E.
Abstract:: Pathogenic mycobacteria are important agents causing human disease. Mycobacterium avium subsp. hominissuis (M. avium) is a species of recalcitrant environmental pathogen. The bacterium forms robust biofilms that allow it to colonize and persist in austere environments, such as residential and commercial water systems. M. avium is also an opportunistic pathogen...
Resource Type:: Article

Nonmuscle myosins II-B and Va are components of detergentresistant membrane skeletons derived from mouse forebrain

Creator:: Ishmael, Jane E., Safic, Masa, Amparan, David, Vogel, Walter K., Pham, Tuyen, Marley, Kevin, Filtz, Theresa M., and Maier, Claudia S.
Abstract:: Myosins are actin-based molecular motors that may have specialized trafficking and contractile functions in cytoskeletal compartments that lack microtubules. The postsynaptic excitatory synapse is one such specialization, yet little is known about the spatial organization of myosin motor proteins in the mature brain. We used a proteomics approach to determine...
Resource Type:: Preprint and Article
Full Text:: -5783 Fax: (541) 737-3999 Email: jane.ishmael@oregonstate.edu and Claudia S. Maier, Ph.D

A Multiplex Biomarker Approach for the Diagnosis of Transitional Cell Carcinoma from Canine Urine

Creator:: Bracha, Shay, McNamara, Michael, Hilgart, Ian, Milovancev, Milan, Medlock, Jan, Goodall, Cheri, Wickramasekara, Samanthi, and Maier, Claudia S.
Abstract:: Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome...
Resource Type:: Article

Effects of low and high dose intraarticular tiludronate on synovial fluid and clinical variables in healthy horses—a preliminary investigation

Creator:: Duesterdieck-Zellmer, Katja F., Moneta, Lindsey, Ott, Jesse F., Larson, Maureen K., Gorman, Elena M., Hunter, Barbara, Löhr, Christiane V., Payton, Mark E., Morré, Jeffrey T., and Maier, Claudia S.
Abstract:: To determine effects of intraarticularly administered tiludronate on articular cartilage in vivo, eight healthy horses were injected once with tiludronate (low dose tiludronate [LDT] 0.017 mg, n = 4; high dose tiludronate [HDT] 50 mg, n = 4) into one middle carpal joint and with saline into the contralateral joint....
Resource Type:: Article
Full Text:: the paper. • Barbara Hunter and Claudia S. Maier performed the experiments, contributed reagents

Structural and functional analysis of the finished genome of the recently isolated toxic Anabaena sp WA102

Creator:: Brown, Nathan M., Mueller, Ryan S., Shepardson, Jonathan W., Landry, Zachary C., Morré, Jeffrey T., Maier, Claudia S., Hardy, F. Joan, and Dreher, Theo W.
Abstract:: Background: Very few closed genomes of the cyanobacteria that commonly produce toxic blooms in lakes and reservoirs are available, limiting our understanding of the properties of these organisms. A new anatoxin-a-producing member of the Nostocaceae, Anabaena sp. WA102, was isolated from a freshwater lake in Washington State, USA, in 2013...
Resource Type:: Article

A freshwater cyanophage whose genome indicates close relationships to photosynthetic marine cyanomyophages

Creator:: Dreher, Theo W., Brown, Nathan, Bozarth, Connie S., Schwartz, Andrew D., Riscoe, Erin, Thrash, Cameron, Bennett, Samuel E., Tzeng, Shin-Cheng, and Maier, Claudia S.
Abstract:: Bacteriophage S-CRM01 has been isolated from a freshwater strain of Synechococcus and shown to be present in the upper Klamath River valley in northern California and Oregon. The genome of this lytic T4-like phage has a 178,563 bp circular genetic map with 297 predicted protein-coding genes and 33 tRNA genes...
Resource Type:: Article

Metabotypes with elevated protein and lipid catabolism and inflammation precede clinical mastitis in prepartal transition dairy cows

Creator:: Zandkarimi, F., Vanegas, J., Fern, X., Maier, C. S., and Bobe, G.
Abstract:: Clinical mastitis (CM), the most prevalent and costly disease in dairy cows, is diagnosed most commonly shortly after calving. Current indicators do not satisfactorily predict CM. This study aimed to develop a robust and comprehensive mass spectrometry-based metabolomic and lipidomic workflow using untargeted ultra-performance liquid chromatography high-resolution mass spectrometry for...
Resource Type:: Article
Full Text:: CITATIONS SEE PROFILE Claudia S Maier Oregon State University 124 PUBLICATIONS 2,415 CITATIONS

ScholarsArchive@OSU

Label-Free Proteomics Assisted by Affinity Enrichment for Elucidating the Chemical Reactivity of the Liver Mitochondrial Proteome toward Adduction by the Lipid Electrophile 4-hydroxy-2-nonenal (HNE)

Protein modifications by electrophilic lipoxidation products: Adduct formation, chemical strategies and tandem mass spectrometry for their detection and identification

¹⁸O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes

Surface-exposed proteins of pathogenic mycobacteria and the role of cu-zn superoxide dismutase in macrophages and neutrophil survival

Nonmuscle myosins II-B and Va are components of detergentresistant membrane skeletons derived from mouse forebrain

A Multiplex Biomarker Approach for the Diagnosis of Transitional Cell Carcinoma from Canine Urine

Effects of low and high dose intraarticular tiludronate on synovial fluid and clinical variables in healthy horses—a preliminary investigation

Structural and functional analysis of the finished genome of the recently isolated toxic Anabaena sp WA102

A freshwater cyanophage whose genome indicates close relationships to photosynthetic marine cyanomyophages

Metabotypes with elevated protein and lipid catabolism and inflammation precede clinical mastitis in prepartal transition dairy cows

Limit your search

Academic Affiliation

Creator

Date

Decade

File Format

Language

License

Peer Reviewed

Resource Type

Rights Statement

Search Constraints

Search Results

Limit your search