Historians and sociologists of science often identify the efflorescence of social stud ies of science with the work of postwar American intellectuals such as Robert K. Merton and Thomas S. Kuhn. They often also refer to the views of Michael Polanyi (1891-1976) on the roles of tacit knowledge, apprenticeship, social...
Background: Osteosarcoma (OSA) is the most common primary bone tumor of dogs and carries a poor prognosis
despite aggressive treatment. An improved understanding of the biology of OSA is critically needed to allow for
development of novel diagnostic, prognostic, and therapeutic tools. The surface-exposed proteome (SEP) of a
cancerous cell...
Pathogenic mycobacteria are important agents causing human disease. Mycobacterium avium subsp. hominissuis
(M. avium) is a species of recalcitrant environmental pathogen. The bacterium forms robust biofilms that allow it to
colonize and persist in austere environments, such as residential and commercial water systems. M. avium is also an
opportunistic pathogen...
Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome...
Hydrologic processes control much of the export of organic matter and nutrients from
the land surface. It is the variability of these hydrologic processes that produces variable
patterns of nutrient transport in both space and time. In this paper, we explore how
hydrologic ‘‘connectivity’’ potentially affects nutrient transport. Hydrologic connectivity...
Snowpack base temperatures vary during accumulation and diurnally. Their measurement
provides insight into physical, biological and chemical processes occurring at the snow/soil interface.
Recent advances in Raman-spectra instruments, which use the scattered light in a standard
telecommunications fiber-optic cable to infer absolute temperature along the entire length of the fiber,...
The Critical Depth Hypothesis formalized by Sverdrup in 1953 posits that
vernal phytoplankton blooms occur when surface mixing shoals to a depth shallower than a
critical depth horizon defining the point where phytoplankton growth exceeds losses. This
hypothesis has since served as a cornerstone in plankton ecology and reflects the...
Koi herpesvirus (KHV) infection is associated with high mortalities in both common carp (Cyprinus carpio carpio) and koi carp (Cyprinus carpio koi) worldwide. Although acute infection has been reported in both domestic and wild common carp, the status of KHV latent infection is largely unknown in wild common carp. To...
The previously suggested protection from microbial attack of ripening nectar by the addition of glucose oxidase by the common honey bee, Apis mellifera L., has been found to occur in 9 other eusocial Hymenoptera from 3 superfamilies. The antibacterial effect results from the accumulation of hydrogen peroxide produced by the...
The hepatotoxic alkaloids known to occur in tansy ragwort (Senecio jacobaea L.) are also present in honey produced from the nectar of this species. These alkaloids, which include senecionine, seneciphvlline, jacoline, jaconine, jacobine, and jacozine, are potentially carcinogenic, mutagenic and teratogenic and may pose health hazards to the human consumer.