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Filtering by: Creator Layton, Robert D. Remove constraint Creator: Layton, Robert D. Resource Type Dissertation Remove constraint Resource Type: Dissertation Rights Statement In Copyright - Educational Use Permitted Remove constraint Rights Statement: In Copyright - Educational Use Permitted

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  • Timescales and tectonics of oceanic plateaus : long-term evolution of Ontong Java Nui and Rio Grande Rise

    Creator:
    Davidson, Peter C.
    Abstract:
    Oceanic plateaus are regions of overthickened oceanic crust and are often thought to form from the interaction of mantle plumes with oceanic lithosphere. These regions can cover vast areas of the ocean basins and represent a highly elevated magmatic flux relative to normal mid-ocean ridge spreading. Oceanic plateaus are considered...
    Resource Type:
    Dissertation
    Full Text:
    ., Asael, D., Planavsky, N.J., Francois, R., McKenzie, N.R., Erba, E., Crowe, S.A., 2021. Pulsed

  • New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

    Creator:
    Overacker, Ross D.
    Abstract:
    Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
    Resource Type:
    Dissertation
    Full Text:
    -rich DNA. (A) Actinomycin D (4.1) was tested at 0.03, 0.10, 0.20, 0.40, 1.00, 2.00, and 3.00 µM. (B

  • Boosting Intracellular Delivery of mRNA Therapeutics

    Creator:
    Patel, Siddharth D.
    Abstract:
    Intracellular delivery of mRNA holds great potential for vaccine and therapeutic discovery and development. This is realized by the preeminent role mRNA is playing in the record-breaking pace of SARS-CoV-19 vaccine development. Recent advances in chemical modifications of mRNA have enabled high-efficiency gene expression with superior spatiotemporal control while eliminating...
    Resource Type:
    Dissertation
    Full Text:
    . Oleh Taratula, Dr. Susan Tilton, and Dr. Robert Allen for their time and interdisciplinary advice. I

  • Emergent Properties of Animal Social Networks: Five Stories in Five Systems

    Creator:
    Devan-Song, E. Anne
    Abstract:
    Animals aggregate and interact in nonuniform and nonrandom patterns, which lead to group level characteristics that have important evolutionary and ecological consequences. Network analysis provides a useful conceptual framework for linking animal interactions at all scales from dyads to communities, to populations and ecosystems. Despite exciting theoretical and applied advances...
    Resource Type:
    Dissertation
    Full Text:
    networks illustrating different topologies (B-D