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Filtering by: Creator Sukhatme, Gaurav S. Resource Type Dissertation Subject Antibacterial agents

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Creator:

Joshi, Pranav R.

Abstract:

Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram-positive bacteria, was incorporated into novel block copolymer constructs and tested for retained antibacterial activity. Covalent coupling was achieved by chemical modification of the N-terminal isoleucine to introduce a thiol group. Thiolated nisin derivatives were then linked to poly[ethylene...

Resource Type:

Dissertation

Full Text:

great times I had in Corvallis and to room-mates Gaurav Bajaj, Prashant Wadhwa and Chandan Sarkar for