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Filtering by: Creator Oyler-McCance, Sara J. Remove constraint Creator: Oyler-McCance, Sara J. Resource Type Dissertation Remove constraint Resource Type: Dissertation Subject Bacterial genetics Remove constraint Subject: Bacterial genetics

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  • Recombination, resistance, and drug discovery in Chlamydia

    Creator:
    Sandoz, Kelsi
    Abstract:
    The intracellular life cycle of Chlamydia has been difficult to study due to the inability to genetically manipulate the bacteria. As a result, indirect methods have been employed to study the pathogen and the aspects that contribute to its unique intracellular life cycle. A wide variety of laboratory adapted strains,...
    Resource Type:
    Dissertation
    Full Text:
    source of fun and encouragement over the years and I’d like to thank them (Val Elias, Sara Weeks, Hency

  • Understanding chlamydial biology through genome sequencing and comparative genomics

    Creator:
    Jeffrey, Brendan
    Abstract:
    The human pathogen Chlamydia trachomatis displays different phenotypes between serovars both in vivo and in vitro. The study of chlamydial biology has been hampered by the lack of a tractable genetic system. Here, chlamydial isolates with known phenotypes as well as strains generated though recombination were fully sequenced to address...
    Resource Type:
    Dissertation
    Full Text:
    and comparative genomics of isolates from rectal or cervical sites of serovar G, E, and J revealed

  • An investigation of carbon and nitrogen metabolism through a genomic analysis of the genus Nitrobacter

    Creator:
    Starkenburg, Shawn R.
    Abstract:
    The chemolithoautotrophic nitrite oxidizing bacteria (NOB) participate in the biogeochemical cycling of nitrogen by catalyzing and conserving energy from the oxidation of nitrite (NO₂-) to nitrate (NO₃-) via a nitrite oxidoreductase (NXR). The main objective of this work was to comparatively annotate and analyze the genome sequences of Nitrobacter winogradskyi...
    Resource Type:
    Dissertation
    Full Text:
    : ___________________________________________________________ Peter J. Bottomley The chemolithoautotrophic nitrite oxidizing bacteria (NOB) participate

  • Characterization of the genomic islands from tetracycline-resistant Chlamydia suis

    Creator:
    Dugan, Jae
    Abstract:
    Tetracycline (Tet)-resistant strains of Chlamydia suis were isolated from swine farms in the Midwest. The isolation of the resistant strains was significant because Tet is an antibiotic used to treat infections by veterinarians and doctors. One of the tetracycline (Tet)-resistant strains, R19, was able to survive in Tet up to...
    Resource Type:
    Dissertation