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Filtering by: Creator Green, Dale Resource Type Dissertation Subject Binding sites (Biochemistry)

Characterization and photoaffinity labeling of the muscarinic acetylcholine receptor

Creator:

Cremo, Christine

Resource Type:

Dissertation

Full Text:

is distinguished pharmacologically as muscarinic (Dale, 1914; Purves, 1976; Magazanik, 1976). It is
Biophysical basis of macromolecular assembly in the dynein cargo attachment complex

Creator:

Hall, Justin Daniel

Abstract:

Cytoplasmic dynein is an ATP-dependent, microtubule-based molecular motor involved in the positioning and trafficking of cellular cargo. The cargo binding sub-domain of dynein contains the natively disordered intermediate chain (IC) and the homodimeric light chains (Tctex1, LC8 and LC7). The structure and stoichiometry of this complex, how the light chains...

Resource Type:

Dissertation

Full Text:

, Michael Freitag and Christopher Mathews, I would like to thank Rick Faber and Dale Tronrud for distinct
Site-specific labeling of the cardiac glycoside receptor Na⁺,K⁺-ATPase : synthesis of a C-17 side group photoaffinity label ; Relationship of cardioactive steroid structure and conformation to biological activity

Creator:

Deffo, Tamboue Esaie

Abstract:

In an effort to isolate and characterize cardiac glycosides C-17 binding site(s), we have synthesized different affinity and photoaffinity C-17 side chain probes. These probes were screened for their ability to inhibit Na⁺,K⁺-ATPase enzyme, a pharmacological receptor of cardiac glycosides. The enzyme was isolated from hog kidney. Screening of these...

Resource Type:

Dissertation

ScholarsArchive@OSU

Characterization and photoaffinity labeling of the muscarinic acetylcholine receptor

Biophysical basis of macromolecular assembly in the dynein cargo attachment complex

Site-specific labeling of the cardiac glycoside receptor Na⁺,K⁺-ATPase : synthesis of a C-17 side group photoaffinity label ; Relationship of cardioactive steroid structure and conformation to biological activity

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