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Filtering by: Creator Hipkins, Valerie D. Resource Type Dissertation Subject Cancer -- Chemoprevention

A novel mechanism of chemoprevention by sulforaphane : inhibition of histone deacetylase

Creator:

Myzak, Melinda C.

Abstract:

Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...

Resource Type:

Dissertation

Full Text:

- Fageeh, Philip Tong, Chris Larsen, Robert Weston, Roland Corden, Maryam Mousaoui, Gayle Orner, Valerie
Mechanisms of inhibition of chemical carcinogenesis by indole-3- carbinol in the rat

Creator:

Stresser, David M.

Resource Type:

Dissertation

Full Text:

, Kelly Munger, Andy Muehlbauer, Diane Foster, Melani Savage, Christian Ahrens, Jennifer Sharp, Valerie