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Filtering by: Creator Burley, Stephen K. Remove constraint Creator: Burley, Stephen K. Resource Type Dissertation Remove constraint Resource Type: Dissertation Subject DNA-protein interactions Remove constraint Subject: DNA-protein interactions

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  • The mechanism of interaction of the linker histone with DNA and nucleosomes

    Creator:
    Ellen, Thomas Patrick
    Abstract:
    This dissertation examines the interaction of the linker histone with DNA and with nucleosomes. The first goal of the project was to characterize the interaction of the linker histone with DNA. Three factors previously reported to influence the linker histone's interaction with DNA were examined: ratio of linker histone to...
    Resource Type:
    Dissertation
    Full Text:
    support he has shown me during the course of this work. Thanks also go to Dr. Christopher K. Mathews

  • Binding and assembly of H5 (and the globular domain of H5) onto DNA

    Creator:
    Carter, George John
    Abstract:
    In order to better characterize linker histone interactions with DNA, avian erythrocyte-specific linker H5 and the trypsin-resistant globular domain of H5 (GH5) were used in DNA binding studies. To begin, H5 displayed a considerably higher binding affinity for DNA than the isolated globular domain (GH5), supporting the importance of the...
    Resource Type:
    Dissertation