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  • The effects of versene on dividing sea urchin eggs

    Creator:
    Hanson, James Charles
    Abstract:
    Developing sea urchin eggs (Strongylocentrotus purpuratus), reared at 15° C, were subjected to single 15-minute treatments with disodium versenate in calcium-free sea water, applied at 10-minute intervals, from 4 minutes after insemination to the second cleavage. These versene pulses produced specific degrees of retardation in the mitotic process and delayed...
    Resource Type:
    Dissertation

  • Dissecting mechanics of chromosome segregation and cleavage furrow induction

    Creator:
    Chen, Wei
    Abstract:
    Accurate chromosome segregation and cell cleavage are critical to maintaining genomic integrity. Both events involve the spindle apparatus, but the exact mechanics is as puzzling as the contradicting models proposed in the last two centuries. In this dissertation, current prevailing models of chromosome segregation and cell cleavage are tested using...
    Resource Type:
    Dissertation